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Global Translational Medicine Prognostic indicators and management of SAP

5. Conclusion 2. Wysocki AP, Carter CR. Acute pancreatitis. Surgery (Oxford).
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SAP remains a serious pathology, despite advancements in
therapeutics and resuscitation techniques. It is primarily a doi: 10.1016/j.mpsur.2007.01.004
medical emergency and ideally necessitates management 3. Uomo G, Rabitti PG, Laccetti M, et al. Predictive evaluation
in an intensive care unit under the supervision of a of acute necrotizing pancreatitis: Results of a prospective
multidisciplinary team. Surgical intervention is typically study. Presse Med. 1995;24(5):263-266.
reserved for cases involving local complications, mainly 4. Banks PA, Bollen TL, Dervenis C, et al. Classification
those of a septic nature, as well as for the treatment of biliary of acute pancreatitis--2012: revision of the Atlanta
etiology. Prevention of nosocomial infection must be an classification and definitions by international consensus.
integral part of the therapeutic strategy since some studies Gut. 2013;62(1):102-111.
have reported a mortality rate of 28.4% due to infectious doi: 10.1136/gutjnl-2012-302779
hospitalism in SAP cases. Following an episode of SAP,
97
the outcome is sometimes marked by the appearance 5. Hebuterne X, Schneider S. Artificial nutrition in acute
of functional sequelae, a phenomenon increasingly pancretitis. Réanimation. 2008;17(5):462-471.
recognized and more prevalent among patients who have doi: 10.1016/j.reaurg.2008.04.003
undergone surgery. Other factors predictive of these 6. Whitcomb DC. Clinical practice. Acute pancreatitis. N Engl
3
sequelae should be investigated, and long-term monitoring J Med. 2006;354(20):2142-2150.
of patients with such outcomes is essential.
doi: 10.1056/NEJMcp054958
Acknowledgments 7. Haney JC, Pappas TN. Necrotizing pancreatitis: Diagnosis and
management. Surg Clin North Am. 2007;87(6):1431-1446, ix.
None.
doi: 10.1016/j.suc.2007.08.013
Funding 8. Uomo G, Pezzilli R, Gabbrielli A, et al. Diagnostic assessment

None. and outcome of acute pancreatitis in Italy: Results of a
prospective multicentre study. ProInf-AISP: Progetto
Conflict of interest informatizzato pancreatite acuta, Associazione Italiana
Studio Pancreas, phase II. Dig Liver Dis. 2007;39(9):829-837.
The authors declare that they have no competing interests.
doi: 10.1016/j.dld.2007.05.009
Author contributions 9. Werge M, Novovic S, Schmidt PN, Gluud LL. Infection
Conceptualization: Haddadi Saïd, Rezki Touati increases mortality in necrotizing pancreatitis: A systematic
Data curation: Ali Baba, Imène Khadidja Bakalem, Nora review and meta-analysis. Pancreatology. 2016;16(5):698-707.
Graidia doi: 10.1016/j.pan.2016.07.004
Writing – original draft: Haddadi Saïd 10. Werner J, Ühl W, Büchler M. Acute pancreatitis. In: Current
Writing – review & editing: Haddadi Saïd, Rabah Ourdane, Surgical Therapy. 8 ed. Philadelphia PA: Cameron JL; 2004.
th
Ladjel Khelafi, Yasmina Yahia Messaoud, Rezki Touati p. 459-469.
Ethics approval and consent to participate 11. Masamune A, Kikuta K, Hamada S, et al. Clinical
practice of acute pancreatitis in Japan: An analysis of
Not applicable. nationwide epidemiological survey in 2016. Pancreatology.
2020;20(4):629-636.
Consent for publication
doi: 10.1016/j.pan.2020.04.013
Not applicable.
12. Larvin M, McMahon MJ. APACHE-II score for
Availability of data assessment and monitoring of acute pancreatitis. Lancet.
1989;2(8656):201-205.
Not applicable.
doi: 10.1016/s0140-6736(89)90381-4
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Volume 3 Issue 2 (2024) 10 doi: 10.36922/gtm.2480