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Global Translational Medicine                                    Retrobulbar and sub-Tenon’s local anesthesia




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            Figure  3.  Graphs  illustrating the  relationship  between  patient and  surgeon  satisfaction (A)  and  between  patient pain  scores  and  surgeon
            satisfaction (B). Identical scores are represented by a single dot in each graph.

            preparation after sedation, but the retrobulbar block was   of 2.4, with seven patients scoring above 3. These findings
            administered before sterile preparation. This approach   suggest that sub-Tenon’s anesthesia is generally effective
            could save preincisional time with sub-Tenon’s block, as   and safe, with the potential to become a preferred method
            preoperative preparation can commence immediately after   for vitreoretinal surgeries in the future. Surgeons reported
            sedation. Future studies should investigate the timing of   high satisfaction with sub-Tenon’s anesthesia, citing
            surgical  protocols  when  using  sub-Tenon’s  anesthesia,   its advantages in terms of patient comfort and surgical
            which allows the surgeon to scrub and proceed directly to   experience. In this study, patients’ pain levels were assessed
            local injection and surgery.                       only during and immediately after  surgery. The study
                                                               exclusively investigated STB without comparing it with
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              Lai et al.  reported that patients receiving either sub-
            Tenon’s or retrobulbar anesthesia experience little or no   other anesthesia methods, and postoperative pain was not
                                                               measured.
            pain during and after vitreoretinal surgery; however,
            patients in the sub-Tenon’s group reported lower pain   A detailed study on anesthesia for 25-gauge vitrectomy
            levels the day after surgery.                      compared retrobulbar, sub-Tenon’s, and medial canthus
                                                               episcleral anesthesia methods, focusing on intraoperative
              Another study compared trans-sub-Tenon’s retrobulbar
            block (TSTRB), sub-Tenon’s block (STB), and peribulbar   and postoperative pain levels. Remarkably, none of the
                                                               patients, regardless of the anesthesia type used, reported
            block (PBB) in vitreoretinal surgeries, evaluating analgesia,
            akinesia,  intraoperative  pain,  and  postoperative  pain.   any postoperative pain or discomfort. This result indicates
                                                               that all three anesthesia techniques effectively managed
            TSTRB,  extending  STB  into  the  retrobulbar  space,  was   pain throughout the vitrectomy, providing a pain-free
            the most effective in achieving akinesia and prolonging   postoperative experience for the patients involved. 33
            postoperative analgesia. Notably, two patients receiving STB
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            reported moderate postoperative pain, whereas patients   In a study by Xu et al.,  patients undergoing pars plana
            in the other groups reported only mild pain. No patients   vitrectomy with sub-Tenon’s anesthesia reported less pain
            in the TSTRB group required postoperative analgesia.   than those receiving retrobulbar anesthesia during surgery
            Another notable finding was that the postoperative pain   and on the first postoperative day. In addition, sub-Tenon’s
            score for patients receiving STB was higher than the other   anesthesia was more effective in inducing akinesia and
            two groups. The study concluded that TSTRB is preferable   controlling eye movements compared to retrobulbar
            in both sub-Tenon’s and peribulbar anesthesia.  However,   anesthesia. However, they did not administer supplemental
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            we did not examine the TSTRB technique in our study.  IV sedation, possibly contributing to increased discomfort
                                                               in the retrobulbar group. IV sedation, often a combination
              Alpay  et  al.  evaluated sub-Tenon’s anesthesia in   of opioid and/or benzodiazepine, is typically used to
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            comparison to retrobulbar anesthesia, concluding that it   enhance patient comfort and reduce intraoperative stress
            effectively controls pain during vitreoretinal surgery and   by inducing retrograde amnesia. This approach can help
            could serve as an alternative to retrobulbar anesthesia.   patients relax, reduce anxiety, and minimize movement
            However, postoperative pain was not measured in this study.  during surgery. However, it is not without risks, as it
              Franco  et al.   assessed  pain  levels  in  patients   requires an anesthesiologist monitoring of heart rate and
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            administered sub-Tenon’s anesthesia during vitreoretinal   blood pressure and preparation for potential complications,
            surgery. Patients reported a mean postoperative pain score   including apnea, airway obstruction, allergic reactions,


            Volume 3 Issue 4 (2024)                         5                               doi: 10.36922/gtm.3900
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