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Global Translational Medicine                                    Retrobulbar and sub-Tenon’s local anesthesia



            drowsiness, and disorientation. Without IV sedation,   study on cataract surgery, STB was associated with lower
            introducing the needle around the eye, particularly in the   pain scores.  A separate study showed that although
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            retrobulbar space, can be very uncomfortable and painful   the need for resedation was lower with the retrobulbar
            for the patient. Consequently, the results of both this and   technique, the sub-Tenon’s group reported higher patient
            our study suggest that comparisons between the efficacy   satisfaction during surgery. 24
            of retrobulbar injection and sub-Tenon’s technique may   Although STB is known to be less effective in inducing
            be influenced by the presence or absence of IV sedation.    akinesia compared to other anesthetic techniques, this
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            Similarly, Haider et al.  compared topical, sub-Tenon’s, and   did not impact surgeon performance in our study. An
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            retrobulbar  anesthesia for  pars plana  vitrectomy  without   experienced surgeon can stabilize the globe using probes
            supplemental IV sedation, finding that topical anesthesia   inserted into the trocars; however, this level of proficiency
            was the least painful method. Although topical anesthesia   may be challenging for less experienced trainees. In our
            showed the lowest pain scores, retrobulbar anesthesia, with   study,  the  factor  most  affecting  surgeon  satisfaction  was
            a mean perioperative pain score of 10.87 and a postoperative   the level of perceived patient discomfort. This patient-
            score of 13.73, was deemed the most convenient.
                                                               reported  discomfort  had  a  notable  impact  on  surgeon
              In our sub-Tenon’s group, we added a preliminary step   satisfaction, underscoring the significance of patient
            involving the subconjunctival injection. The resulting   comfort in enhancing the overall surgical experience.
            chemosis, although potentially disruptive to surgical   One of the limitations of the current study is the selection
            procedures, could be alleviated by conjunctival massage,   bias resulting from the nonrandomized allocation of patients
            which helped provide more reliable pain relief, particularly   into groups. The unequal distribution of patients in the
            during conjunctival manipulation at the start of surgery
            and during trocar placement. This massage step could   two study groups and the small sample size are significant
                                                               limitations. We also recognize that the lack of blinding
            fill the time gap needed to achieve complete anesthetic   could introduce bias, as evaluators may have known the
            infiltration in the retrobulbar space, thus enhancing   participants’ group assignments. In addition, the duration
            patient comfort and allowing surgery to proceed sooner.
            Alternatively, the time required for this massage could   of the vitreoretinal surgeries per anesthesia group was not
            offset the time saved between the retrobulbar block and   recorded, and we did not exclude patients with diabetes or
            sterile preparation. Therefore, it is unclear if sub-Tenon’s   hypertension, which could influence perceived pain levels.
            capsule anesthesia is faster than retrobulbar anesthesia.   5. Conclusion
            However,  like  the  sub-Tenon’s  method,  the  retrobulbar
            technique also requires massage to disperse the anesthesia   Our results suggest that sub-Tenon’s anesthesia, combined
            and prevent elevated intraocular pressure, especially when   with subconjunctival injection, has similar efficacy to
            hyaluronidase is not used.                         retrobulbar block in patients undergoing pars plana
                                                               vitrectomy in our cohort. Sub-Tenon’s anesthesia may
              We conducted the STB using a sharp 27-gauge needle,   serve as a suitable alternative to retrobulbar anesthesia
            a common practice in clinical settings. However, some   in some vitreoretinal surgery patients. Compared with
            experts advocate using an angiocatheter due to its superior   the retrobulbar technique, sub-Tenon’s anesthesia is less
            safety profile, as its design may lower complication risks   invasive, involves a shorter learning curve, and has a lower
            during the procedure. Nevertheless, a significant drawback   risk of complications and fewer preparatory steps.
            of the angiocatheter is that it often requires a conjunctival
            incision, which could extend the procedure duration and   Acknowledgments
            be uncomfortable for the patient.
                                                               None.
              All our surgeries involved two painful steps—namely,
            intraoperative indentation and laser photocoagulation—  Funding
            which were well tolerated by patients in both groups.   None.
            When ocular anesthesia faded during prolonged surgeries,
            necessitating reinjection, the sub-Tenon’s technique was   Conflict of interest
            more  feasible.  In  one  study  comparing  sub-Tenon’s  and
            retrobulbar anesthesia for trabeculectomy in glaucoma   The authors declare that they have no competing interests.
            surgery, additional sedation was more frequently required
            in the retrobulbar group, as was postoperative analgesia.   Author contributions
            This study also showed that the sub-Tenon’s method   Conceptualization:  Nazanin  Ebrahimiadib,  Fardin
            required a lower volume of local anesthetic.  In another   Yousefshahi
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            Volume 3 Issue 4 (2024)                         6                               doi: 10.36922/gtm.3900
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