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Global Translational Medicine                                     Recent community-based CVD interventions



            over several decades. These historical efforts have paved   and 70% higher mortality rates from CVD compared to
            the way for modern interventions which will be discussed   the general population. The unique culture, history, and
            in the following sections.                         legal status of indigenous communities provide unique
                                                               challenges and opportunities for community-based health
            4. Health equity and community-based               interventions. 26
            cardiovascular interventions
                                                                 In addition, rural communities face their own unique
            Disparities in cardiovascular health across racial, ethnic,   challenges in managing cardiovascular risk. Lack of
            and socioeconomic lines remain a major public health   both specialized and primary care physicians and other
            crisis in America. Black, non-black Hispanic, indigenous,   clinicians, lack of medical supplies, long travel distances
            and rural communities in America experience significant   to hospitals, and high incidence of food deserts contribute
            health disparities and are at a notably higher risk for   to a stark urban/rural divide in markers of cardiovascular
            CVD. Compared to White Americans, Black Americans   health. Although poverty level is a strong moderating
            are nearly twice as likely to have major CVD risk factors   variable, rural areas have higher CVD death rates than
            such as obesity, type 2 diabetes, and hypertension, and to   their urban counterparts across the board. These disparities
            experience major CVD including ischemic heart disease,   are the most pronounced in the southern US, where rural
            heart failure, and stroke.  In addition, non-Hispanic Black   populations experience over double the rate of CVD
                               20
            individuals are 33% more likely to die of CVD than non-  mortality.  Community-based health interventions are
                                                                       27
            Hispanic white individuals.  Recent data from 43,000   critical pieces in boosting healthcare within underserved
                                   21
            persons also confirmed that Black women and men have   communities and bridging gaps in health equity. Crucially,
            the highest long-term cardiovascular mortality of any racial   these interventions must consider the differences in specific
            or ethnic group, even after adjusting for atherosclerotic   patient populations to be effective. In African–American
            CVD  risk  scores  and  coronary  artery  calcium.   These   communities,  involving  non-medical  community
                                                    22
            disparities can be attributed to social determinants of   members such as hairdressers and pastors has been shown
            health,  including  healthcare  access,  low  socioeconomic   to increase medication adherence as well as primary and
            status, food deserts, racism-related stress, and lack of trust   secondary health outcomes.  Medication adherence,
                                                                                       16
            in the healthcare system. 23                       notably reduced in Black communities, is a major risk
              For Hispanic communities, language barriers provide   factor that can be attributed to lower education levels, lack
            their own complications. Furthermore, a lack of Hispanic   of social support and culturally competent care, and high
            clinicians, lower socioeconomic markers among Hispanic   costs. Many of these factors can be directly addressed with
            immigrant communities, and food deserts caused by   a community-based intervention involving other persons
            geographic disparities add to the challenges to reduce   in addition to physicians. A notable successful example of
            CVD burden in this population.  Large meta-analyses   combining health professionals with community leaders
                                       24
            have found that Hispanic Americans have similar levels   is the Los Angeles Barbershop Blood Pressure Study,
            of minor CVD as White Americans but much higher    where pharmacist-led interventions in Black-owned
                                                                                                      18
                                  20
            incidence of type 2 diabetes.  However, a unique challenge   barber shops drastically reduced blood pressure.  On the
            in studying Hispanic populations in America is their   other hand, one shortcoming of not involving physicians
            incredible diversity, both genetically and socio-culturally.   in  community-based  initiatives  is  a  lack  of  integration
            The term “Hispanic” is an umbrella classification that   between different types of healthcare workers and actual
            includes individuals of varying national origins, racial   clinical care. 28
            backgrounds, migration histories, and socioeconomic   Recent innovations include the use of geographic
            statuses. This heterogeneity poses methodological   information system mapping to determine the optimal
            challenges in cardiovascular research, as findings from one   locations of so-called “trusted spaces” – community centers
            subgroup (e.g., Mexican Americans) may not be applicable   such as barber shops and nail salons where staff can provide
            to another (e.g., Puerto Ricans, Cubans, or Central   evidence-based care to maximize the positive impacts.  In
                                                                                                          29
            Americans). Consequently, broad  generalizations may   Hispanic communities, programs targeting language and
            undermine the credibility of study findings. As a result,   cultural barriers have been particularly effective. Thirteen
            some studies may find substantial CVD disparities, while   weeks of behavioral classes on healthy habits taught
            others find none. 24,25                            in Spanish to patients with type  2 diabetes decreased
              Indigenous US communities also suffer from higher   hemoglobin A1c (HbA1c) from an average of 7 – 6.3% after
            rates of CVD than their non-Hispanic White counterparts.   1 year.  This is especially significant considering diabetes
                                                                    30
            Indigenous men and women have, respectively, 30%   is the main cardiovascular disparity that is consistently

            Volume 4 Issue 3 (2025)                         53                          doi: 10.36922/GTM025170040
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