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International Journal of Bioprinting Bioprinting for large-sized tissue delivery

Figure 3. 3D printing, stability, and deformation behavior of GP architectures. (A) A temperature sweep from 5 to 25°C during the reduction process of
GP hydrogel. (B) A 20-min time sweep at a constant temperature of 19°C. (C) Viscosity curve of GP hydrogel; smooth filament extrusion from the nozzle
(inset). (D) The designed models and the corresponding printed architectures with different filling patterns. (E) Structural stability test of the printed
architectures during long-term culture. Four independent fields with more than 20 filaments were calculated for each time point. (F) Cyclic pinch and (G)
stretch of the bioprinted architectures with circular ring geometry. Statistical analysis in (E) is performed using ANOVA with Tukey’s HSD post-hoc test.
Scale bars: 5 mm (D); 500 μm (E–G). Abbreviations: N.S.: no statistical significance; GP: Gelatin methacryloyl/poly(ethylene glycol) diacrylate; G’: Storage
modulus; G”: Loss modulus; ANOVA: one-way analysis of variance; and HSD: honestly significant difference.

Volume 10 Issue 5 (2024) 435 doi: 10.36922/ijb.3898