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Matrix-assisted pulsed laser evaporation-deposited rapamycin thin films
of rapamycin were maintained after the MAPLE angiogenic Effects of Mammalian Target of Rapamycin
process; L929 mouse fibroblasts grown on Inhibitors in a Mouse Model of Oxygen-induced Retinopathy.
MAPLE-deposited rapamycin-PVP thin films Biol Pharm Bull, 37:1838–42. DOI: 10.1248/bpb.b14-00487.
exhibited lower cell viability and proliferation 6. Krishnadev N, Forooghian F, Cukras C, et al., 2011,
rates than cells grown on borosilicate glass control Subconjunctival Sirolimus in the Treatment of Diabetic
surfaces. The MAPLE-fabricated thin films may Macular Edema. Graefe’s Arch Clin Exp Ophthalmol,
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This work was supported by a grant of the Ministry 9. Maulvi FA, Soni TG, Shah DO, 2016, A Review on
of Research and Innovation, CNCS – UEFISCDI, Therapeutic Contact Lenses for Ocular Drug Delivery. Drug
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Drug Administration and should not be construed DOI: 10.1016/j.jconrel.2015.01.023.
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