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International Journal of Bioprinting Internally-crosslinked ADA/Alg/Gel bioinks

Figure 4. Rheological characterization and in vitro stability analysis of ADA/Alg/Gel hydrogels. (A) Storage modulus (G′; continuous line) and loss
modulus (G″; dotted line) of ADA/Alg/Gel hydrogels as a function of angular frequency (0.1–100 rad/s) at 37°C (n = 3). (B) Elastic modulus (E) derived
from frequency sweep test (n = 3). (C) Wet weight variation (%) of ADA-Alg/Gel hydrogels measured at 1, 3, 7, 14, and 21 days after incubation at 37°C
(n = 3). (D) Dry weight loss (%) of ADA/Alg/Gel hydrogels measured at 1, 7, 14, and 21 days after incubation at 37°C (n = 3). In all graphs, the samples
are ADA/Alg/Gel_50/50/0 (red), ADA/Alg/Gel_50/47.5/2.5 (orange), ADA/Alg/Gel_50/45/5 (yellow), ADA/Alg/Gel_50/40/10 (light blue), ADA/Alg/
Gel_50/35/15 (blue), ADA/Alg/Gel_50/30/2 (purple), and ADA/Alg/Gel_50/25/25 (green). *p < 0.05,**p < 0.01, ***p < 0.001, and ****p < 0.0001 indicate

statistically significant difference with ADA/Alg/Gel_50/50/0. Abbreviations: Alg: Alginate; ADA: Alginate dialdehyde; Gel: Gelatin.

Volume 10 Issue 6 (2024) 555 doi: 10.36922/ijb.4014