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           microstructure, production costs, and initial investment.   of the  part  (Figure  2C). This is emphasized  when the
           Notably, the  limited  rating for post-processing   desired application of the technologies in its current state
           and mechanical  properties may indicate  that some   (Figure 5C) or if their main shortcomings are overcome
           stakeholders are not completely aware of their importance.   (Figure  5D) is considered.  The development  of new
           Alternative, this may also suggest that old, well-known   products  only  increases  in  the  medical  field  once  the
           AM limiters are either being subsided by the advances of   current issues are addressed, while design only considers
           the technology or accepted as an inevitable part of these   the use of AM to modify existing products in the same
           processes. Other barriers mentioned  during the survey   scenario. Consequently, although personalized medicine
           include limited standardization, few materials available,   is the main initiator of AM uptake, enhancement of the
           software reliability, complex machine certification or the   technological state of AM may lead to new opportunities.
           manual labor involved in de-powdering (specific to metal   Materials and mechanical properties were shown to
           AM processes), and post-processing.                 be critical for the success of the device and may constrain
               Current and future perspectives were analyzed   the use of 3D printing  (Figure  2B  and  C); however,
           by surveying  the  likelihood  of further  incorporating   these are not perceived as a huge disadvantage, with only
           or increasing the presence of AM given the state of the   microstructure  mentioned  as a  constraint  (Figure  5B).
           technologies as of now (Figure 5C and Table S17) or   Feedstock for most systems is highly specialized, which
           in a hypothetical future (Figure  5D  and  Table S18)   requires specific manufacturing processes and control. As
           where the previously mentioned limitations were eased.   the technology is still emerging, the limited demand for
           While similar core interests are shared in both scenarios,   bulk feedstock and poor guidance on quality management
           differences can be observed between respondent groups.   and traceability has reduced the number of suppliers and
           The state of existing processes seems to be a tool to design   materials, resulting in material availability being critical
           new products and develop new techniques,  although   to AM  expansion [2,9,40] .  Based  on this  survey,  it  seems
           the  latter  varies  with expertise.  In the  case  of design   likely that the respondents are mainly concerned about
           respondents, the design of new products, 50%, should be   material processing rather than raw feedstock availability.
           the main area of focus for this technology; however, the   Partly, this may have been caused by the specificity of the
           pursuit of product modification, designing new products   medical field where there has been a preference for the use
           and development  of new techniques through  AM is   of a reduced number of base materials considered as gold
           shared between  manufacturing  (33.3%, 33.3%, and   standards (i.e., Titanium alloys or PEEK) . In contrast
                                                                                                  [45]
           22.2%, respectively)  and medical  (23.5%, 17.6%, and   to material availability and given the intrinsic connection
           52.9%,  respectively).  Specific  areas  where  3D  printing   between microstructure and mechanical properties is thus,
           could be effectively used included: Introduction of novel   surprising to see the disconnection showed between these
           structures, research, and any field where customization is   two parameters in the current survey. Nevertheless, much
           required or desired.                                work has been done by the research community on the link
               The  general  trend undergoes a  slight  shift  in  the   between system inputs and final part properties for powder
           hypothetical  case that current limitations  are subsided   bed fusion [39,46,47]  and material extrusion [48,49] , two of the
           with the design of new products being the main focus area,   most used systems by the respondents. Regardless of the
           followed by a similar interest in product modification and   advances indicated by the academic community, it seems
           technique development. Small variations in interest take   likely that concerns about anisotropy, delamination,  or
           place in academia, manufacturing and medical experts;   variations in mechanical behavior from well-established
           however, a more radical shift occurs in design. For once,   traditional techniques [29,50]  are still affecting the uptake of
           these  professionals did not consider  the  use of AM to   these technologies.
           modify products in the current state of the technology;   Numerous reviews on  AM  state waste reduction
           nevertheless, 28.6% agree that this should be the main   and sustainability as main advantages over conventional
           avenue alongside the design of new products and     processes, generally, as a result of reduced waste material,
           prototyping. Nevertheless, the Fisher exact test did not   less energy intensive and polluting  manufacturing
           reveal a significant link between expertise or these fields.  processes,  efficient  designs  and  decentralization  of
               Based on this survey, the main potential        the supply chain, which could result in significant cost
           observed in medicine seems to be consistently focused   savings [3,4,38,51-53] . While interest in using sustainability as a
           on  personalization  and  control  of  the  final  design   marker for system selection has been shown (Figure 2A),
           (Figure  4A    and  5A). Similarly, lead time reduction   waste  reduction  was not  considered  an  advantage
           is clearly perceived as a benefit for the uptake of AM.   (Figure  5A), with cost selected as the most consistent
           Thus, it is likely that all experts agree with the general   AM concern throughout the questionnaire. In this regard,
           trends reported in literature; nevertheless, it appears   it  must be said that  current  AM technologies  are  still
           that  personalization is not likely critical  to the success   classed as emerging and perhaps lack the infrastructure

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