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International Journal of Bioprinting 3D bioprinted vascularized tissue models

Ref. [42] [43] [40] [44] [46] [47] [48] [49] [50] [28] [53] [54] [55] [59] [60] [61] [62] [63] [65] [66]

Major achievements Construction of thick (>1 cm) and long-lasting (>6 weeks) pre-vascularized tissues within customized perfusion chips Creation of a freestanding, perfusable, and functional in vitro vascular model with endothelium lining in the luminal wall exhibiting representative vascular functions, including selective permeability, anti-platelets/leukocyte adhesion, and self-remodeling in response to physiological shear stress and directional angiogenesis Const
Table 2. Summary of 3D-bioprinted vascularized in vitro models for different applications

Cell types b HNDFs, HBMSCs, HUVECs HUVECs HUVECs, HCASMCs, HDFs HUVECs, HNDFs HepaRG, HUVECs HepG2, HUVECs HepG2, HUVECs, HNDFs HepG2, EA. hy 926 HepG2, LX-2, HUVECs PTECs PTECs, GMECs RPTECs, HUVECs Caco-2, HK-2, GEs Patient- derived GBM cells, HUVECs Patient-derived GBM cells, hAstro, hMG, hPericytes, HUVECs Patient-derived GBM cells, HUVECs A549, HUVECs, HDFs SK-MEL-28, HUVECs MCF-7, HUVECs SK-M

Biomaterials a PF-127, gelatin-fibrinogen bioink PF-127, VdECM/alginate hybrid bioink PF-127, VdECM/alginate hybrid bioink Fibrinogen-based com- posite bioink, alginate Liver dECM, gelatin PF-127, GelMA-fibrin bioink Alginate-methylcellulose bioink, collagen-fibrin- gelatin bioink Collagen, alginate, gelatin Liver dECM, gelatin PF-127, gelatin-fibrin bioink PF-127/PEO ink, gelatin- fibrin bioink PF-127, kidney dECM/ alginate hybrid bioink P

Bioprinting approaches Sacrificial Coaxial Embedding + coaxial Coordinated pat- terning Coordinated pat- terning Sacrificial Coaxial Coaxial Coordinate pat- terning Sacrificial Sacrificial Coaxial Coaxial Coordinated pat- tering Sacrificial Sacrificial Coordinated pat- terning Embedding + coaxial Coaxial Embedding + coaxial

Target Vessel Liver Kidney Tumor

Volume 9 Issue 5 (2023) 21 https://doi.org/10.18063/ijb.748