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International Journal of
            Population Studies                                                  Health-related quality of life and mortality



            providing a more comprehensive understanding than that   Our results indicate that HRQoL can serve as a
            afforded by summary components alone.              significant indicator of future adverse health outcomes,
              Physical functioning exhibited the strongest association   supporting clinical, social, and policy decisions. For
            with mortality. A decline in physical functions can stem from   instance, in Australia, the SF-12 has been integrated into
            various health conditions, potentially explaining the increased   the routine application of Patient Reported Outcome
            risk of premature death. However, our study adjusted for the   Measures as a strategic goal for the Australian health
            number of chronic diseases at the beginning of the follow-up,   system (Williams et al., 2016). As an abbreviated version
            which mitigated this effect. Lower physical functioning   of SF-36, SF-12 assesses health-related QoL across physical
            at baseline may have contributed to increased sedentary   and mental health dimensions. Improved prediction of
            behavior, increased risk of falls, as well as diminished social   premature death risk among older individuals facilitates
            interactions, autonomy, and independence among older   better clinical monitoring and targeted interventions
            individuals. These combined factors can exacerbate health   aimed at reducing this risk. Reducing the testing costs
            issues and lead to premature mortality. This association   can alleviate the economic burden linked to health issues,
            reinforces Evans and Stoddart’s (1990) model, highlighting   in the context of a rapidly aging population (Phyo et al.,
            functionality as a critical component of health, influenced by   2021). These possibilities align with Evans and Stoddart’s
            disease, behavioral, and biological aspects.       (1990) model, which transcends traditional healthcare
                                                               boundaries to incorporate health status and functionality as
              A prospective cohort study involving 30,043      key elements in understanding and delivering healthcare.
            participants (Shishehbor et al., 2006) found that physical
            functioning accounted for 47% of the relationship between   Previous  studies  conducted  across  different  countries
            socioeconomic status and mortality. This underscores the   have generally shown that healthy aging does not adversely
            importance of analyzing HRQoL as a predictor of mortality   affect HRQoL, suggesting that it is feasible to enjoy a high
            in  Brazil,  where  approximately  70%  of  older  individuals   QoL and well-being over extended periods (Tourani et al.,
            had an individual monthly income of <420 United States   2018). Maintaining a healthy lifestyle in old age is essential
            dollars in 2020 (Brazil, 2020).                    to prevent chronic diseases, improve physical functioning
                                                               and well-being, as well as support independence, autonomy,
              In addition, our study identified associations between   and active aging (Lima et al., 2011). Understanding which
            mortality and social, emotional, and mental health   aspects of QoL are most affected by comorbidities in the
            domains. A systematic review conducted in Asia found that   older population is crucial for developing strategies to
            strong social support, having a spouse or partner, living   minimize these impacts and promote dignified aging with
            with family, maintaining a large social network, frequent   good health and well-being.
            contact with family and friends, emotional support, and
            satisfaction with social connections were linked to fewer   A  high  score  in  PC  indicates  minimal  physical
            depressive symptoms among non-institutionalized older   limitations, high energy levels, and health rated as
            adults (Mohd et al., 2019). Furthermore, a cohort study with   “excellent.” Meanwhile, a high score in MC reflects frequent
            a 20-year follow-up demonstrated a significant association   positive feelings, absence of psychological distress, and no
            between social isolation/loneliness and mortality (Beller &   impairment in social activities due to emotional issues,
            Wagner, 2018). Two systematic reviews and meta-analyses   along with health rated as “excellent” (Ware & Gandek,
            in low-  and middle-income countries also revealed an   1998). Therefore, HRQoL serves as a measure of the
            association  between  depression  and  premature  death   impact of diseases on individual lives, and lower HRQoL
            among older adults (Brandão et al., 2019; Wei et al., 2019).   scores  indicate  impaired  well-being and predict all-
            These findings highlight the importance of considering   cause mortality. Consequently, clinical, social, and policy
            social and emotional aspects when assessing the health of   interventions are essential to manage CNCDs.
            the elderly population.                              The strengths of this study include its retrospective cohort
              In a large cohort study of women who initially reported   design with a representative sample of the older population,
            poor physical and mental health but improved during   along with comprehensive information and variables that
            follow-up, the risk of mortality was similar to that of women   enabled adjustments for potential confounders. These
            whose HRQoL remained consistently good (Kroenke et al.,   findings are unprecedented in Brazil and Latin America
            2008). Positive lifestyle changes, particularly increased   concerning various dimensions of health and QoL assessed
            physical  activity,  were  associated  with  improvements   using a validated and widely employed standardized
            in both PC and MC scores. Adopting healthier lifestyles   instrument that serves as a predictor of mortality in older
            and pursuing preventive measures can enhance health,   adults. Although this study has limitations, they were
            improve QoL, and reduce the risk of premature mortality.  minimal and did not compromise the validity of the results.

            Volume 11 Issue 1 (2025)                        68                        https://doi.org/10.36922/ijps.1928
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