Page 53 - IMO-1-1
P. 53
Innovative Medicines & Omics Antioxidant nanomedicines for therapies
Postdoctoral Program for Innovative Talents (Grant No. doi: 10.1038/nri1312
BX20230389), and China Postdoctoral Science Foundation 8. Winterbourn CC. Reconciling the chemistry and biology of
(Grant No. 2022M723274). reactive oxygen species. Nat Chem Biol. 2008;4(5):278-286.
Conflict of interest doi: 10.1038/nchembio.85
9. Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. Glutathione
The authors declare no conflicts of interest.
metabolism and its implications for health. J Nutr.
Author contributions 2004;134(3):489-492.
doi: 10.1093/jn/134.3.489
Conceptualization: All authors
Visualization: Bowen Yang 10. Mates JM, Perez-Gomez C, Nunez de Castro I. Antioxidant
Writing – original draft: Bowen Yang enzymes and human diseases. Clin Biochem. 1999;32(8):595-603.
Writing – review and editing: Jianlin Shi doi: 10.1016/s0009-9120(99)00075-2
Ethics approval and consent to participate 11. Pisoschi AM, Pop A. The role of antioxidants in the
chemistry of oxidative stress: A review. Eur J Med Chem.
Not applicable. 2015;97:55-74.
doi: 10.1016/j.ejmech.2015.04.040
Consent for publication
12. Sies H. Oxidative stress: Oxidants and antioxidants. Exp
Not applicable. Physiol. 1997;82(2):291-295.
Availability of data doi: 10.1113/expphysiol.1997.sp004024
13. Mittal M, Siddiqui MR, Tran K, Reddy SP, Malik AB.
Not applicable.
Reactive oxygen species in inflammation and tissue injury.
References Antioxid Redox Signal. 2014;20(7):1126-1167.
doi: 10.1089/ars.2012.5149
1. Finkel T, Holbrook NJ. Oxidants, oxidative stress and the
biology of ageing. Nature. 2000;408(6809):239-247. 14. Leyane TS, Jere SW, Houreld NN. Oxidative stress in
ageing and chronic degenerative pathologies: Molecular
doi: 10.1038/35041687
mechanisms involved in counteracting oxidative stress and
2. Cai H, Harrison DG. Endothelial dysfunction in chronic inflammation. Int J Mol Sci. 2022;23(13):7273.
cardiovascular diseases: The role of oxidant stress. Circ Res. doi: 10.3390/ijms23137273
2000;87(10):840-844.
15. Chouchani ET, Pell VR, Gaude E, et al. Ischaemic accumulation
doi: 10.1161/01.res.87.10.840 of succinate controls reperfusion injury through mitochondrial
3. Phull AR, Nasir B, Haq IU, Kim SJ. Oxidative stress, ROS. Nature. 2014;515(7527):431-435.
consequences and ROS mediated cellular signaling in doi: 10.1038/nature13909
rheumatoid arthritis. Chem Biol Interact. 2018;281:121-136.
16. Giacco F, Brownlee M. Oxidative stress and diabetic
doi: 10.1016/j.cbi.2017.12.024 complications. Circ Res. 2010;107(9):1058-1070.
4. Barnham KJ, Masters CL, Bush AI. Neurodegenerative doi: 10.1161/CIRCRESAHA.110.223545
diseases and oxidative stress. Nat Rev Drug Discov.
2004;3(3):205-214. 17. Lee SF, Harris R, Stout-Delgado HW. Targeted antioxidants
as therapeutics for treatment of pneumonia in the elderly.
doi: 10.1038/nrd1330 Transl Res. 2020;220:43-56.
5. Ratliff BB, Abdulmahdi W, Pawar R, Wolin MS. Oxidant doi: 10.1016/j.trsl.2020.03.002
mechanisms in renal injury and disease. Antioxid Redox
Signal. 2016;25(3):119-146. 18. Galley HF. Oxidative stress and mitochondrial dysfunction
in sepsis. Br J Anaesth. 2011;107(1):57-64.
doi: 10.1089/ars.2016.6665
doi: 10.1093/bja/aer093
6. Fiocchi C. Inflammatory bowel disease: Etiology and 19. Cuzzocrea S, Riley DP, Caputi AP, Salvemini D. Antioxidant
pathogenesis. Gastroenterology. 1998;115(1):182-205.
therapy: A new pharmacological approach in shock,
doi: 10.1016/s0016-5085(98)70381-6 inflammation, and ischemia/reperfusion injury. Pharmacol
7. Lambeth JD. NOX enzymes and the biology of reactive Rev. 2001;53(1):135-159.
oxygen. Nat Rev Immunol. 2004;4(3):181-189. 20. Forman HJ, Zhang H. Targeting oxidative stress in disease:
Volume 1 Issue 1 (2024) 47 doi: 10.36922/imo.2527

