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Innovative Medicines & Omics Antioxidant nanomedicines for therapies

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Figure 37. (A and B) Schematic illustration of nasopalatal defect treatment using CeO nanoparticles-embedded poly-(methyl methacrylate) orofacial
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prosthesis. Reproduced with permission from Jin et al. Copyright © 2023, Elsevier.
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Prussian blue nanoparticle has been approved by U.S. activity (Figure 39). Such a composite nanocatalyst was
FDA for detoxification of radioactive cesium or thallium demonstrated to be efficient in preventing acute radiation
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contamination. Zhang et al. also used mesenchymal syndrome with a small administration dose.
stem cell membrane to coat Prussian blue nanoparticle
for improving their bone marrow targeting favoring 12.9. Heavy metal poisoning treatment
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radioprotection. Other antioxidant nanocatalyst such Exposure to heavy metals such as lead (Pb), cadmium (Cd),
as CeO nanoparticles have also been used for protecting and mercury (Hg) can seriously affect human health, by
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hematopoietic system against ionizing irradiation. directly damaging tissue or overproducing ROS. Typically,
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Han et al. deposited Mn O on the surface of CeO Pb poisoning can induce neurasthenia, kidney dysfunction
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nanoparticles, significantly elevating the antioxidative and cardiovascular diseases. 495-497 2, 3-dimercaptosuccinic
Volume 1 Issue 1 (2024) 43 doi: 10.36922/imo.2527