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Innovative Medicines & Omics Herbal remedies for diabetes mellitus

studies, for instance, are valuable for identifying potential traditional medicine, healthcare systems can develop more
mechanisms of action. However, they may not fully effective and sustainable strategies to improve diabetes
replicate the intricate physiological interactions that occur outcomes and overall public health.
in living organisms. These studies often concentrate on
specific molecular targets or pathways, overlooking the fact Acknowledgments
that diabetes is a multifaceted condition affecting multiple None.
organs and systems. Furthermore, although animal models
provide useful insights, they may not accurately represent Funding
the pathophysiology of diabetes in humans. Laboratory
animals are typically maintained on standardized diets and None.
have limited physical activity, which does not reflect the Conflict of interest
diverse lifestyles and environmental exposures of human
populations. These factors can significantly influence The author declares no conflict of interest.
disease progression and treatment efficacy. Moreover,
diabetes-induced in animals through chemical or genetic Author contributions
manipulation may not fully capture the pathophysiological Conceptualization: Divya Sharma
complexity of human diabetes, especially T2DM, which Visualization: Asma Praveen, Ashish Vishwakarma, Faizul
involves insulin resistance, impaired insulin secretion, Hasan
and genetic pre-disposition. Another challenge in the Writing – original draft: Ashish Vishwakarma
field is the variability in extract preparation, dosage, and Writing – review & editing: Ashish Vishwakarma, Vasudev
treatment duration, which can make it difficult to compare Biswas, Faizul Hasan, Divya Sharma
study outcomes across different investigations. Finally,
further research is required to assess the long-term safety Ethics approval and consent to participate
and effectiveness of various medicinal plants in human
populations. Not applicable.
7. Conclusion Consent for publication
DM is a complex and widespread health challenge that Not applicable.
requires a multifaceted approach for effective management. Availability of data
With distinct classifications, such as T1DM, T2DM,
GDM, and MODY, each form necessitates tailored clinical Not applicable.
strategies. Early and accurate diagnosis through HbA1c
testing, fasting plasma glucose measurement, and OGTT References
test is crucial for timely intervention. While conventional 1. Srivastava SP. Editorial: Current understanding of
treatments such as insulin therapy, oral hypoglycemic complications associated with diabetes. Front Clin Diabetes
agents, and lifestyle modifications remain the cornerstone Healthc. 2023;4:1-3.
of diabetes management, emerging innovations – including doi: 10.3389/fcdhc.2023.1338656
gene therapy, nanotechnology, and stem cell research –
offer promising advancements. In addition, medicinal 2. Kharroubi AT. Diabetes mellitus: The epidemic of the
plants such as G. sylvestre, M. charantia, and T. foenum- century. World J Diabetes. 2015;6(6):850.
graecum present valuable complementary therapeutic doi: 10.4239/wjd.v6.i6.850
potential. 3. Diabetes DOF. Diagnosis and classification of diabetes
A holistic strategy that integrates prevention, early mellitus. Diabetes Care. 2010;33(SUPPL 1):S62-S69.
diagnosis, and innovative treatments is critical in tackling doi: 10.2337/dc10-S062
the global diabetes epidemic. Public health initiatives 4. Patel DK, Kumar R, Laloo D, Hemalatha S. Diabetes
should emphasize education, lifestyle interventions, and mellitus: An overview on its pharmacological aspects and
equitable access to healthcare to reduce diabetes prevalence reported medicinal plants having antidiabetic activity. Asian
and associated complications. Furthermore, the integration Pac J Trop Biomed. 2012;2(5):411-420.
of artificial intelligence-driven technologies and digital
therapeutics enhances self-management and personalized doi: 10.1016/S2221-1691(12)60067-7
care, empowering patients to take an active role in disease 5. International Diabetes Federation. Five questions on the IDF
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Volume 2 Issue 2 (2025) 31 doi: 10.36922/imo.7520