Page 47 - ITPS-8-1

INNOSC Theranostics and
Pharmacological Sciences Ketamine for cocaine use disorder

receptor systems. In: Van Dongen AM, editor. Biology of the receptor antagonist ketamine: A randomized, crossover
NMDA Receptor. Frontiers in Neuroscience. CRC Press/Taylor trial. Mol Psychiatry. 2017;22(1):76-81.
& Francis; 2009. Available from: https://www.ncbi.nlm.nih. doi: 10.1038/mp.2016.39
gov/books/NBK5280 [Last accessed on 2024 Jul 30].
26. Le TT, Cordero IP, Jawad MY, et al. The abuse liability of
15. Wang YQ, Huang YH, Balakrishnan S, et al. AMPA and ketamine: A scoping review of preclinical and clinical
NMDA receptor trafficking at cocaine-generated synapses. studies. J Psychiatr Res. 2022;151:476-496.
J Neurosci. 2021;41(9):1996-2011.
doi: 10.1016/j.jpsychires.2022.04.035
doi: 10.1523/JNEUROSCI.1918-20.2021
27. Palamar JJ, Fitzgerald ND, Grundy DJ, Black JC, Jewell JS,
16. Gautam CS, Mahajan SS, Sharma J, Singh H, Singh J. Cottler LB. Characteristics of poisonings involving ketamine
Repurposing potential of ketamine: Opportunities and in the United States, 2019–2021. J Psychopharmacol (Oxf).
challenges. Indian J Psychol Med. 2020;42(1):22-29.
2023;37(8):802-808.
doi: 10.4103/IJPSYM.IJPSYM_228_19
doi: 10.1177/02698811221140006
17. Club Drugs. Available from: https://www.nyc.gov/site/doh/ 28. Simmler LD, Li Y, Hadjas LC, Hiver A, van Zessen R,
health/health-topics/club-drugs.page [Last accessed on Lüscher C. Dual action of ketamine confines addiction
2024 Jul 31]. liability. Nature. 2022;608(7922):368-373.
18. Chaves TV, Wilffert B, Sanchez ZM. Overdoses and deaths doi: 10.1038/s41586-022-04993-7
related to the use of ketamine and its analogues: A systematic
review. Am J Drug Alcohol Abuse. 2023;49(2):141-150. 29. Schoepfer KJ, Strong CE, Saland SK, Wright KN, Kabbaj M.
Sex-and dose-dependent abuse liability of repeated
doi: 10.1080/00952990.2022.2132506
subanesthetic ketamine in rats. Physiol Behav. 2019;203:60-69.
19. Maltbie EA, Gopinath KS, Howell LL. Effects of ketamine doi: 10.1016/j.physbeh.2017.10.021
treatment on cocaine-induced reinstatement and disruption
of functional connectivity in unanesthetized rhesus monkeys. 30. Bonaventura J, Lam S, Carlton M, et al. Pharmacological and
Psychopharmacology (Berl). 2019;236(7):2105-2118. behavioral divergence of ketamine enantiomers: Implications
for abuse liability. Mol Psychiatry. 2021;26(11):6704-6722.
doi: 10.1007/s00213-019-05204-4
doi: 10.1038/s41380-021-01093-2
20. Xu L, Nan J, Lan Y. The nucleus accumbens: A common
target in the comorbidity of depression and addiction. Front 31. Elersič K, Banjac A, Živin M, Zorović M. Behavioral
Neural Circuits. 2020;14:37. sensitization and tolerance induced by repeated treatment
with ketamine enantiomers in male Wistar rats. PLoS One.
doi: 10.3389/fncir.2020.00037
2024;19(3):e0299379.
21. Sinha R. The clinical neurobiology of drug craving. Curr doi: 10.1371/journal.pone.0299379
Opin Neurobiol. 2013;23(4):649-654.
32. Commissioner O of the. FDA Approves New Nasal Spray
doi: 10.1016/j.conb.2013.05.001 Medication for Treatment-Resistant Depression; Available
22. Fitzpatrick CJ, Morrow JD. Subanesthetic ketamine Only at a Certified Doctor’s Office or Clinic. FDA; 2020.
decreases the incentive-motivational value of reward-related Available from: https://www.fda.gov/news-events/
cues. J Psychopharmacol Oxf Engl. 2017;31(1):67-74. press-announcements/fda-approves-new-nasal-spray-
medication-treatment-resistant-depression-available-only-
doi: 10.1177/0269881116667709
certified [Last accessed on 2024 Jul 30.
23. Gao Z, Winhusen TJ, Gorenflo M, et al. Repurposing 33. Ketamine for Intractable Headache. Practical Neurology.
ketamine to treat cocaine use disorder: Integration of Available from: https://practicalneurology.com/
artificial intelligence-based prediction, expert evaluation, articles/2022-nov-dec/ketamine-for-intractable-headache
clinical corroboration and mechanism of action analyses. [Last accessed on 2024 Jun 29.
Addiction. 2023;118(7):1307-1319.
34. Rothberg RL, Azhari N, Haug NA, Dakwar E. Mystical-type
doi: 10.1111/add.16168
experiences occasioned by ketamine mediate its impact on
24. Dakwar E, Levin F, Foltin RW, Nunes EV, Hart CL. The at-risk drinking: Results from a randomized, controlled
effects of subanesthetic ketamine infusions on motivation trial. J Psychopharmacol (Oxf). 2021;35(2):150-158.
to quit and cue-induced craving in cocaine-dependent doi: 10.1177/0269881120970879
research volunteers. Biol Psychiatry. 2014;76(1):40-46.
35. Dakwar E, Anerella C, Hart CL, Levin FR, Mathew SJ,
doi: 10.1016/j.biopsych.2013.08.009
Nunes EV. Therapeutic infusions of ketamine: Do the
25. Dakwar E, Hart CL, Levin FR, Nunes EV, Foltin RW. Cocaine psychoactive effects matter? Drug Alcohol Depend.
self-administration disrupted by the N-methyl-D-aspartate 2014;136:153-157.

Volume 8 Issue 1 (2025) 41 doi: 10.36922/itps.4458