Page 103 - ITPS-8-3
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INNOSC Theranostics and
            Pharmacological Sciences                                       Biomarkers for early heart risks in pre-eclampsia



               based therapies can be ensured by collaboration with   6. Practical applications for post-partum
               specialized care teams and cardiologists.       care
            (iii) Healthcare  integration. Transforming information
               into  practice  requires the  incorporation of  CV   This section describes useful applications that close the
               follow-up measures into post-partum care programs.   knowledge gap between science and practical application,
               It is crucial to implement a systematic strategy that   with an emphasis on enhancing post-partum care for
               includes post-partum visits specifically aimed at CV   women who have previously experienced pre-eclampsia.
               health. Scheduled screenings, lifestyle counseling, and   (i)  Home blood pressure monitoring. All women with
               risk stratification evaluations may be included in these   pre-eclampsia who receive a home blood pressure
               sessions. It is equally crucial to educate primary care   monitor  are  better  equipped  to  monitor  their  CV
               physicians, midwives, and obstetricians on the long-  health on their own. Accurate readings are guaranteed
               term CV consequences of pre-eclampsia. Support at   and early hypertension detection can be realized
               the policy level to guarantee the long-term viability   through sufficient training on correct usage and
               of these integrated care models can improve results   interpretation. By providing prompt medical advice
               and compliance. Longitudinal monitoring can be     based on patient-reported data, telehealth services can
               further facilitated by telemedicine and digital health   further complement this strategy.
               platforms, which can close gaps in treatment delivery   (ii)  Post-partum care packages. Long-term CV health can
               and access.                                        be improved with a structured care package designed
                                                                  for  pre-eclamptic  women.  These  packages  ought
            5. Pragmatic approaches                               to  contain  structured  physical  activity  suggestions,
                                                                  mental health support, and dietary instructions that
            Several pragmatic approaches are presented in the     prioritize cardioprotective diets and lower sodium
            following:                                            intake. Regular check-ins can be made easier with the
            (i)  Proposed program of testing. It is crucial to evaluate   help  of  telehealth  services,  guaranteeing  adherence
               CV risk factors, such as blood pressure, lipid profiles,   and quickly resolving new issues.
               and glucose tolerance as soon as possible after giving   (iii)  Community-based  follow-up  programs.
               birth. The link between delivery and long-term     Collaborations with  local healthcare professionals
               CV health can be closed with annual physicals that   provide regular and easily accessible follow-up care.
               concentrate on these metrics and the use of home   Programs could consist of community support groups,
               blood pressure monitoring for early identification.  educational courses, and recurring health evaluations.
            (ii)  Financial implications. It is important to stress how   These programs encourage participation and remove
               cost-effective early detection and preventative care   obstacles to care, especially for marginalized groups.
               are. Evidence indicates that systematic post-partum
               follow-up could significantly lower the long-term   7. Innovative diagnostic tools
               financial burden associated with controlling CVDs,   7.1. Point-of-care testing (POCT)
               despite the initial investment appearing hefty. Existing
               post-partum care programs’ insights highlight how   A major development in early diagnostic techniques is
               feasible such a strategy is.                    POCT, which provides quick and accurate identification
            (iii) Implementation and oversight. For implementation   of biomarkers linked to pre-eclampsia and CV health
               to be successful, an integrated care route involving   risks. Real-time evaluation of vital parameters, such as
               cardiologists, obstetricians, and primary care doctors   blood pressure, proteinuria, and new biomarkers, such
               is essential. To ensure fair access and participation,   as PlGF and sFlt-1 is made possible by POCT equipment,
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               community  health  workers  and  digital  health   which are portable and easy to use.  Previous research has
               platforms can help with adherence and continuity of   demonstrated the effectiveness of POCT in environments
               care.                                           with low resources, where traditional laboratory
            (iv)  Future trial. To validate these suggested therapies,   infrastructure might not be available.
               extensive, long-term studies are necessary. Pre-  To mitigate maternal and fetal problems, for example,
               eclampsia women’s existing registries are a useful tool   the incorporation of POCT for sFlt-1/PlGF ratio testing
               for obtaining sufficient samples and carrying out long-  has shown promise in stratifying the severity of pre-
               term follow-up research. Evidence-based guidelines   eclampsia. POCT promotes personalized medicine
               would be informed by these trials, improving post-  methods by promoting early detection and intervention,
               partum care and lowering long-term CV morbidity in   which improves outcomes for women who are at risk of
               this susceptible group.                         pre-eclampsia and related CV disorders.  POCT will
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            Volume 8 Issue 3 (2025)                         97                               doi: 10.36922/itps.7839
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