Page 30 - JCBP-2-4

Journal of Clinical and
Basic Psychosomatics Genetic factors and personality disorders

whose characterization extends beyond the limitations of Consent for publication
scales and categories.
Informed consent of the study participants was obtained
The research findings highlighted a notable prevalence of for publishing this work.
concurrent multiple drug use among patients. Furthermore,
the inclusion of smokers among the participants may have Availability of data
influenced the study outcomes. Moreover, it is crucial to Data are available from the corresponding author upon
recognize that studies focusing on substance abuse cannot reasonable request.
be easily generalized to individuals specifically dependent
on heroin. The manner in which personality disorders are References
conceptualized could also impact our findings. 68
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Experimental validation has consistently confirmed Quality of life and personality disorders in heroin abusers.
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whether these characteristics represent an inherent
“addictive personality” that predated drug use, or if they 2. Moustafa AA, Tindle R, Cashel S, Parkes D, Mohamed E,
are a result of drug addiction. One of the limitations of Abo Hamza E. Bidirectional relationship between heroin
69
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the current study is the absence of a control group.
Curr Psychol. 2022;41:5195-5211.
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Conducting prospective studies will help to further 3. Dettmeyer R, Friedrich K, Schmidt P, Madea B. Heroin-
explore the relationship between drug use, genetic factors, associated myocardial damages-conventional and
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Furthermore, personality studies can be complemented
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amalgamation of investigating genetic factors can offer 4. Abed H, Hassona Y. Oral healthcare management in heroin
valuable insights into the intricate connection between and methadone users. Br Dent J. 2019;226(8):563-567.
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Acknowledgements 5. Tolomeo S, Steele JD, Ekhtiari H, Baldacchino A. Chronic
heroin use disorder and the brain: Current evidence and
None. future implications. Prog Neuropsychopharmacol Biol
Psychiatry. 2020;111:110148.
Funding
doi: 10.1016/j.pnpbp.2020.110148
None.
6. Cheng GL, Zeng H, Leung MK, et al. Heroin abuse accelerates
Conflict of interest biological aging: A novel insight from telomerase and brain
imaging interaction. Transl Psychiatry. 2013;3(5):e260.
The authors declare that they have no competing interests.
doi: 10.1038/tp.2013.36
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Ethics approval and consent to participate 2004;28(1):129-139.

The study protocol was authorized by the review boards doi: 10.1016/j.pnpbp.2003.09.029
at the Shanghai Mental Health Center (SHMC), School 9. Ceceli AO, King SG, McClain N, Alia-Klein N,
of Medicine, Shanghai Jiao Tong University. Informed Goldstein RZ. The neural signature of impaired inhibitory
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Volume 2 Issue 4 (2024) 8 doi: 10.36922/jcbp.3890