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Journal of Clinical and
            Basic Psychosomatics                                            Alcohol use disorder relapse: Tools and factors



            2.5. Structural review                             AUDIT is a semi-structured rating scale that assesses

            For structural review, we assessed whether the title   three dimensions: alcohol consumption and frequency,
            accurately reflected the theme and whether the abstract   alcohol  dependence, and  alcohol-related issues, with a
            summarized the key points. The introduction was    total of 10 items. The World Health Organization began
                                                               the collaborative development of AUDIT in 1982. Nearly
            examined for its explanation of the background and   2,000 drinkers from six countries participated in its testing,
            purpose, whereas the logic of the main body was evaluated
            for clarity. The conclusion was assessed to determine   and its use  has been  promoted globally since 1989.  The
            whether it reasonably summarized the key content.  AUDIT was first introduced and translated into Chinese
                                                               by the Institute of Mental Health at Peking University in
            2.6. Methodological review                         1999. It was tested on male workers and cadres in 2000 and
                                                               confirmed to have good reliability and validity in China.
            The literature search process was appraised for    (ii) Diagnostic and Statistical Manual of Mental Disorders,
            comprehensiveness, the screening methods were assessed for   Fifth Edition, Text Revision (DSM-5-TR): According to the
            scientific rigor, and the overall review process was evaluated   DSM-5, AUD severity is classified based on the number of
            to ensure that the quality of the review was maintained.
                                                               clinical symptoms. Two to three symptoms indicate mild
            3. Current situation and assessment                AUD, four to five symptoms indicate moderate AUD, and
            instruments for AUDs                               six or more symptoms indicate severe AUD (Table  2).
                                                               (iii) The ICDs, Tenth Revision, Clinical Modification
            According to the diagnostic criteria of the Diagnostic   (ICD-10-CM): The ICD-10 coding system labels AUDs as
            and Statistical Manual of Mental Disorders (DSM-   follows: F10.10 for mild AUD and F10.20 for moderate and
            5), a patient can be diagnosed with AUD if they have   severe AUD.
            experienced significant distress or impairment due to
            alcohol consumption within 12 months, and meet at least   4. Assessment tools for alcohol relapse
            two of the 11 clinical symptoms outlined. According to the   Patients with AUDs are often prone to relapse after receiving
            International Classification of Diseases (ICD-10), AUDs   treatment and successfully quitting drinking. The relapse
            can be categorized into the following types: acute alcohol   rate of AUDs patients following abstinence is extremely
            poisoning, harmful use of alcohol, alcohol dependence   high, with most relapses occurring within 3  months
            syndrome, alcohol withdrawal syndrome, alcohol-induced   after discharge. The main reason for this is that alcohol-
            psychiatric disorders, alcohol-induced mood disorders,   related cues and the stress induced by consuming even
            alcohol-induced neurocognitive  disorders,  and  other   small amounts of alcohol can significantly undermine the
            related conditions (Table 1).                      patient’s determination to quit and negatively affect their
                                                               quality of life. 11,12  The severity of relapse can be evaluated
            3.1. Current situation of AUDs
                                                               across multiple dimensions,  such as the frequency and
                                           8
            A comparative risk assessment study  in 2018 revealed   amount of alcohol consumption, the degree of alcohol
            that approximately 3 million people worldwide die each   craving, and the impact of relapse on the patient’s daily life
            year due to harmful alcohol use, accounting for 5.3% of   and social functioning.
            all causes of death. In addition, about 132.6 million people
            experience a reduction in life expectancy due to disability   4.1. Current situation of relapse
            caused by alcohol consumption. Drinking has thus become   Research from multiple expert and scholar teams
            one of the leading causes of death, disability, and disease   worldwide indicates that, after professional treatment
            burden globally.  A cross-sectional study  conducted in   and care, the relapse rate for AUD patients who have quit
                         9
                                              10
            2019 reported that the annual prevalence rate of AUDs in   drinking for one year generally remains around 60%. 12-14
            the general population of China was 1.8%, with a lifetime   Studies on the relapse rate of AUD patients in China are
            prevalence rate of 4.4%.                           also ongoing. Zhao et al.  found a relapse rate of 63.7%.
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                                                               A study by Yuan et al.  reported a 1-year relapse rate close
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            3.2. Assessment instruments for AUDs               to 50%, with 27.2% of patients relapsing within 1 month
            The  assessment  of  the  severity  of  AUDs includes  both   of discharge. According to a survey by Wang et al.,  the
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            subjective and objective instruments. Clinically, multiple   relapse rates for AUDs patients who had quit drinking and
            assessment tools, developed by different organizations, are   were discharged from the hospital were 35.1%, 50.3%, and
            often used in combination to comprehensively evaluate   60.3% at 1 month, 3 months, and 6 months, respectively,
            the severity of AUDs in patients. These tools include   with a 6-month mortality rate of 1%. A survey by Shao
            the following: (i) AUD Identification Test (AUDIT): the   et al.  found that relapse occurred between 42 and 75 days
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            Volume 3 Issue 2 (2025)                         13                              doi: 10.36922/jcbp.6559
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