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Journal of Clinical and
            Basic Psychosomatics                                            Alcohol use disorder relapse: Tools and factors



            1. Introduction                                    including China National Knowledge Infrastructure and
                                                               Wanfang, were searched using relevant terms to identify
            Alcohol  use  disorders  (AUDs)  are chronic,  recurrent   Chinese-language literature.
            mental  disorders  characterized  by  compulsive  alcohol
            abuse and a loss of control over alcohol intake.  With   Inclusion  criteria were  established to select literature
                                                     1
            economic development, the incidence of AUDs continues   that  comprehensively  considers studies  from  China  and
            to rise worldwide, now accounting for 4.9% of substance   other countries, focusing on research related to AUDs,
            abusers.  From 2010 to 2012, the drinking rates for men   relapse factors, and care. The selected studies should cover
                  2
            and women over the age of 15 in China were 54.6% and   population characteristics in different regions, the impact
            13.3%,  respectively, with daily  drinking  rates  reaching   of cultural backgrounds on AUDs and relapse, as well as
            25.7% and 10.9%, respectively. These trends pose   corresponding care measures and outcomes. Literature
            significant risks to personal health and social stability.    that was duplicated, of low quality, had unreasonable
                                                          3
            Tucker et al.’s  survey in 2020 showed that approximately   research designs, or solely focused on a single country
                       4
            one-third of the United States population had received a   without  cross-country  comparisons  or comprehensive
            lifelong diagnosis of AUDs. Chou et al.’s  research in 2023   analyses was excluded.
                                            5
            revealed that the prevalence of AUDs in the United States
            was as high as 9.7% in December, whereas in South Korea,   2.2. Data extraction
            it was 7.1%. According to the Global Burden of Disease   Information was extracted from the selected literature,
            2013 Risk Factors Collaborators, approximately 95 million   including patients’ basic information, characteristics of
            people worldwide suffer from alcohol dependence.  While   AUD, relapse-related factors, care measures, and outcomes.
                                                    6
            most patients with AUDs can successfully quit drinking
            after treatment, a considerable number experience relapse   2.3. Comprehensive review
            shortly after discharge, leading to a recurrence of the   The review was conducted from three perspectives:
            disorder.                                          sociodemographic, individual, and social factors.

              Relapse refers to the return to alcohol consumption after   For sociodemographic factors, differences in AUDs and
            successfully quitting during the acute withdrawal period,    relapse across various age, gender, and occupation groups
                                                          7
            despite maintaining abstinence for some time. Various   were examined. For example, young people, due to their
            factors  contribute  to  this  failure  to  control  drinking,   active social lives, have more opportunities to drink. In
            ultimately leading to the restoration of AUDs.  At present,   some occupations, frequent social engagements increase
                                                7
            the  mechanisms  underlying  relapse  in AUD  patients   the risk of relapse.
            remain unclear, but it is well-established that long-term
            heavy drinking causes significant damage to the central   For individual  factors,  the impact of  genetic
            nervous system and leads to various mental disorders.   susceptibility, psychological states (such as anxiety and
            Therefore, accurate assessment of alcohol withdrawal, early   depression), and drinking habits on the disorder and
            identification of relapse risks, and an understanding of the   relapse were explored. For instance, individuals with a
            factors influencing relapse are essential for maintaining   family history of AUD and vulnerable psychological states
            abstinence, reducing relapse rates, and improving patients’   are more likely to relapse.
            quality of life. This review aims to provide an update on   For social factors, the roles of social support systems,
            the latest research regarding established assessment tools   cultural customs, and policies and regulations were
            and  relapse  determinants,  as  well as  to  identify  novel   examined. For example, a strong social support system can
            tools and factors. Our findings may contribute to current   reduce relapse rates, while regions with a strong drinking
            treatment practices and serve as a reference for health-care   culture may present a higher risk for developing AUD.
            professionals in promoting successful abstinence for AUD
            patients.                                          2.4. Content review

            2. Methods                                         The relevance of the literature to care for AUDs and relapse-
                                                               influencing factors was  evaluated.  The review assessed
            2.1. Literature search and selection               whether the literature comprehensively elaborated on the
            PubMed, Web of Science, PsycINFO, and the Cochrane   three types of influencing factors and their corresponding
            Library were searched using terms such as “alcohol use   care strategies. Innovation, such as the identification of
            disorder,” “relapse,” “factors,” and “tools or questionnaires”   new influencing factors or unique care strategies, was also
            for English-language literature published from January   examined. The accuracy of the data was verified to ensure
            1990  to  August  2024.  In  addition,  Chinese  databases,   the reliability of the underlying research.


            Volume 3 Issue 2 (2025)                         12                              doi: 10.36922/jcbp.6559
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