Page 51 - JCBP-3-3

Journal of Clinical and

Basic Psychosomatics

PERSPECTIVE ARTICLE
Integrative pathophysiological and

psychological strategies for Alzheimer’s and
dementia-related disease management

3,4
1,2
S. Kyle Travis * , Sean E. Quisenberry , and Blake A. Terry 1
1 Department of Bioengineering and Medical Device Innovation, MediTerry, Terry Ventures, Tamaroa,
Illinois, United States of America
2 Department of Allied Health Professions, School of Health Sciences, Liberty University, Lynchburg,
Virginia, United States of America
3 Department of Kinesiology, School of Human Sciences, Southern Illinois University-Carbondale,
Carbondale, Illinois, United States of America
4 Human Performance and Sports Technology Laboratory, Southern Illinois University-Carbondale,
Carbondale, Illinois, United States of America

Abstract

As global demographics shift toward an aging population, the urgency for innovative
diagnostic tools to address Alzheimer’s and dementia-related diseases (ADR) has never
been greater. Current methods often miss the opportunity to capture the nuanced
interplay between cognitive decline and emotional health, leaving critical diagnostic
gaps. This paper introduces an integrated approach combining advanced retinal imaging
*Corresponding author: through eye-tracking, reaction-retention testing, and the short recovery-stress scale
S. Kyle Travis
(stravis17@liberty.edu) (SRSS) to provide a holistic evaluation and monitoring system of ADR progression. Retinal
imaging through eye-tracking captures neurodegenerative biomarkers such as saccadic
Citation: Travis SK, Quisenberry
SE, Terry BA. Integrative movements and fixation patterns and offers real-time insights into cognitive processing.
pathophysiological and Reaction-retention tests directly measure short-term memory and processing speed
psychological strategies for while the SRSS evaluates emotional states influencing cognitive health and physical
Alzheimer’s and dementia-related
disease management. J Clin Basic capabilities. These modalities deliver a comprehensive cognitive-emotional profile,
Psychosom. 2025;3(3):45-53. enabling earlier detection and personalized interventions. By synthesizing data across
doi: 10.36922/jcbp.8349 physiological and psychological domains, this approach addresses the multifaceted
Received: December 31, 2024 nature of ADR, providing clinicians with actionable insights into disease management.
These integrative tools also hold promise for scalable applications in routine clinical
Revised: February 19, 2025
and home settings, paving the way for enhanced monitoring, tailored therapies, and
Accepted: February 27, 2025 improved patient outcomes. The proposed framework represents a potential paradigm
Published online: March 18, 2025 shift in ADR diagnostics, offering potential extensions to other neurodegenerative
conditions, including Parkinson’s disease and traumatic brain injuries.
Copyright: © 2025 Author(s).
This is an Open-Access article
distributed under the terms of the
Creative Commons Attribution Keywords: Alzheimer’s disease; Dementia; Neurodegenerative; Biomarkers; Emotion
License, permitting distribution, state; Retinal atrophy
and reproduction in any medium,
provided the original work is
properly cited.
Publisher’s Note: AccScience 1. Introduction
Publishing remains neutral with
regard to jurisdictional claims in The quest for early and accurate detection of Alzheimer’s and dementia-related diseases
published maps and institutional
affiliations. (ADR) is more urgent than ever as the global population ages. Despite advancements in

Volume 3 Issue 3 (2025) 45 doi: 10.36922/jcbp.8349