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Koschny et al. | Journal of Clinical and Translational Research 2024; 10(2): 151-158 153
Table 1. Patients’ characteristics
Parameter Patient #1 Patient #2 Patient #3 Patient #4 Patient #5 Patient #6 Patient #7
Age (years) 73 70 72 31 59 67 74
Sex Male Male Female Female Male Male Male
Tumor Oropharyngeal carcinoma Oropharyngeal Hypopharyngeal Hypopharyngeal Supraglottic Glottic Carcinoma of the
(histopathology) and synchronous carcinoma carcinoma carcinoma carcinoma carcinoma of larynx (squamous cell
supraglottic carcinoma of (squamous cell (squamous cell (squamous cell of the larynx the larynx carcinoma)
the larynx carcinoma) carcinoma) carcinoma) (squamous cell
(squamous cell carcinoma)
carcinoma)
TNM (UICC) pT2 pN2c cM0 R1 cT4 cN0 cM0 cT2 cN0 cM0 cT4 cN2b cM0 pT3 pN3b M0 cT3 cN0 cT3 cN0 cM0
pT2 pN2a cM0 R0 cM0
Oncological Total laryngectomy pRCHT pRCHT ICT + pRCHT Total Tumor pRCHT
treatment modalities and partial resection laryngectomy debulking,
of oropharynx, with neck pRCHT
reconstruction, aRCHT dissection
Additional neoplasia NCSLC*, pT4 cN2 cM0 Prostate cancer, pT3 NCSLC, cT2 cN2 None None. None None
(RCHT 45Gy) pN0 R1 (radical cM0, synchronic
Skin cancer (squamous prostate resection) (RCHT)
cell carcinoma, head/ Squamous cell
neck) pT1 pNx R0 cancer esophagus*
20 cm from incisors
(RCHT)
Abbreviations: NCSLC: Non-small cell lung cancer; RCHT: Radiochemotherapy; TNM: Staging according to T=Primary tumor, N=Lymph node metastases, and M=Distant metastases.
UICC: Union International Contre le Cancer (International Union against Cancer).
Table 2. Synopsis of treatment
Parameter Patient #1 Patient #2 Patient #3 Patient #4 Patient #5 Patient #6 Patient #7
Length of 20 8 20 30 5 30 5
obliteration (mm)
Means of Ring cutter, Ring cutter, ERC Dilatator ERC Dilatator (10F), Ring cutter, EUS cystotome ERC Dilatator (6F),
recanalization ERC-Balloon bougienage (7F), bougienage 5 mm bougienage 5 mm (10F), bouginage bouginage 5 mm
7 mm, 5 mm bougienage 7 mm
bougienage 9 mm
7 mm
Technical success Yes Yes Yes Yes Yes Yes Yes
of recanalization
Number of 8/5 18/4 12 50/47 28/11 17/4 7/5
bougienages/
balloon
dilatations
Final diameter 10 18 15 16 12 16 20
(mm)
Additional Three fcSEMSs, RCHT for Reopening Microsurgical scar fcSEMS, Microsurgical scar Microsurgical scar
measures surgical fistula secondary due to excision, triamcinolone, APC, surgical excision excision
closure, APC tumor re-occlusion APC fistula closure,
triamcinolone
Final outcome Deceased 3 Laryngectomy Normal Salvage Bougienage Bougienage Salvage
month after rejected eating, PEG laryngopharyngectomy ongoing, ongoing, PEG- laryngopharyngectomy
last fcSEMS by patient, removed for esophago- tracheal PEG-independent dependent
implantation palliative care fistula
for osteolytic
infection
Abbreviations: APC: Argon plasma coagulation; fcSEMS: fully covered self-expanding metal stent; PEG: Percutaneous endoscopic gastrostomy; RCHT: Radiochemotherapy.

no other treatments, for 958 days after her last bougienage. One cell cancer, detected 495 days after recanalization. Externally
patient died shortly after recanalization from lung cancer (#1). performed radiotherapy overlapped with the initial radiation
One patient (#2) was treated with definitive radiochemotherapy field, resulting in esophageal wall necrosis with osteomyelitis
for a secondary poorly differentiated esophageal squamous and spinal metal implantation (Figure 4A). The patient was lost
DOI: https://doi.org/10.36922/jctr.23.00116