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Koschny et al. | Journal of Clinical and Translational Research 2024; 10(2): 151-158   155

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                                                                Figure 3. Additive treatments during bouginage. (A) After the eighth
                                                                bougienage of the recanalized esophagus (E), an esophago-tracheal
                                                                fistula became evident in patient #1 (*, left) and was endoscopically
                                                                closed by a fully covered 10 × 100 mm biliary stent (right). (B) To
                                                                widen the entrance into the recanalization below the arytenoid cartilage,
                                                                scar tissue was removed by repeated microsurgery, thereby shifting the
                                                                entrance to the middle (patient #4). (C) Due to recurrent scar formation
        Figure 2. Periprocedural complications. (A) Axial computed   and granulation tissue cytoreductive, argon plasma coagulation therapy
        tomography plane of the upper thorax aperture demonstrates the soft   was applied in patient #7.
        tissue pocket (P) at the plane of the tracheostomy (TS) adjacent to the
        common carotid artery (C), left subclavian artery (S) and left lung. The
        gastric tube (GT) was placed as a placeholder in the esophageal lumen.   Insertion of a feeding tube until repeated bougienages [18] or
        The inset is an image showing the condition after tissue pocket healing   even the temporal placement of a small-diameter covered metal
        5 months later. (B) The time-consuming healing of the tissue pocket (P)   stent (≤10 mm) [13,14] has been reported as approaches to keeping
        delayed the progress of bougienages by approximately 100 days. (C) To   the pharyngoesophageal passage open after recanalization.
        keep the dilated esophageal entrance next to the arytenoid cartilage   However, immediate metal stent insertion did not seem to reduce
        (A) open until subsequent bougienage, two guidewires for two gastric   the  necessity  of subsequent and repeated  bougienages  but was
        tubes were inserted (upper left). Wire-guided and simultaneous insertion   associated with a higher abscess formation rate [13]. In this case
        of the two gastric tubes had to be assisted by Wendl tubes, one in each   series,  fully  covered  self-expanding  metal  stents  (fcSEMSs)
        nostril (upper right), which splinted the pharynx (lower left) and enabled   were  used  only  when  fistulas  coexisted  with  the  recanalized
        the simultaneous insertion of two gastric tubes (lower right).  pharyngoesophageal  channel  and they did not reduce the need
                                                                for repeated  bougienage.  From  our experience,  the  insertion
        due to repeated maneuvers with the endosonography needle   of a gastric tube as a placeholder is highly recommended until
        (patient #4). Needle knife preparation [18] and puncture   the lumen is stable enough to prevent reocclusion. To maintain
        with the hard end of a wire [22], as well as puncture with a   a functional passage, patients needed up to 32 [18] or even 37
        trocar needle from the pharyngeal side [14], as in our cases,   bougienages [4]. In this case series, up to 97 treatment sessions
        have  also  been  reported.  Using  a  stiff  needle  for  puncture   were performed on one patient  who did not agree  to salvage
        from  the  pharyngeal  site  offers  some  advantages  regarding   operation.
        maneuverability, especially in obliterations over a longer   An overall complication  rate of 11% was reported in the
        distance, but still harbors the risk of injuring adjacent and   literature for the applied rendezvous technique [15]. It has been
        vulnerable structures. Blunt preparation from the oral side   reported that mediastinal emphysema [22], pneumothorax [12],
        under fluoroscopic and endoscopic guidance and puncture of   pneumomediastinum  with  periesophageal  abscess formation
        the remaining short segmented soft tissue might be preferable   and cervical osteomyelitis, cervical abscess formation [13], and
        in short-distance occlusions.                           microperforation [19] are mainly managed conservative mode. In
                                                DOI: https://doi.org/10.36922/jctr.23.00116
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