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Journal of Clinical and Translational Research 2024; 10(2): 159-164




                                        Journal of Clinical and Translational Research

                                               Journal homepage: http://www.jctres.com/en/home


        ORIGINAL ARTICLE

        Analysis of the effects of pulsed microcurrent on pain, depression, and

        anxiety in patients with herpes zoster



        Li Wang *, Jingxuan Liu , Jing Wang , Yurong Zhang , Junwu Zhang 3
               1
                             2
                                        1
                                                      1
        1 Department of Scientific Research, Faculty of General Family Medicine, the First Affiliated Hospital of Xi’an Medical University, Xi’an, Shaanxi,
        China,  Department of Health Statistics, Faculty of Public Health, Shaanxi University of Chinese Medicine, Xi’an, Shannxi, China,  Xi’an Aikaier
                                                                                                       3
             2
        Medical Technology Co., Ltd, Xi’an, Shaanxi, China.
        ARTICLE INFO                        Abstract
        Article history:                    Background: Herpes zoster is a common viral skin infection and has a high incidence rate in China.
        Received: October 23, 2023          At present, conventional drugs combined with adjuvant measures are used for treatment. To improve
        Accepted: March 3, 2024             the efficiency and shorten the time of treatment, we propose the use of pulsed microcurrent as a new
        Published Online: April 3, 2024     adjuvant therapy.
                                            Aim: This study aimed to investigate the effects of pulsed microcurrent on pain, depression, and
        Keywords:                           anxiety in patients with herpes zoster.
        Pulsed microcurrent                 Methods: A total of 58 patients with herpes zoster who were admitted to our hospital between April
        Herpes zoster                       and August 2022 were selected as study participants and divided into two groups. The control group
        Pain                                (n = 29) received conventional drug therapy, while the experimental group (n = 29) received pulsed
        Depression and anxiety              microcurrent electrical therapy in combination with conventional drug therapy.
        Impact analysis                     Results:  After  14  days  of  treatment,  the  scores  from  the  visual  analog  scale,  patient  health
                                            questionnaire (PHQ) (i.e., PHQ-9), and generalized anxiety disorder (GAD) assessment (i.e., GAD-7)
        *Corresponding author:              of the experimental group were reportedly significantly lower than those the control group (P < 0.05).
        Li Wang                             Conclusion:  These  findings  suggested  that  pulsed  microcurrent  electrical  therapy  combined  with
        Department of Scientific Research, Faculty of   conventional drug therapy could effectively alleviate the pain, depression, and anxiety symptoms in
        General Family Medicine, the First Affiliated   patients with herpes zoster, highlighting its potential to be widely used in clinical practice.
        Hospital of Xi’an Medical University, Xi’an,   Relevance  for Patients:  Patients  suffering  from  herpes  zoster  may  opt  for  pulsed  microcurrent
        Shaanxi, China                      electrical therapy to effectively alleviate the pain, depression, and anxiety symptoms.
        Email: wangli7828@xiyi.edu.cn

        © 2024 Author(s). This is an Open-Access
        article distributed under the terms of the   1. Introduction
        Creative Commons Attribution-Noncommercial
        License, permitting all non-commercial use,   Herpes zoster is a viral skin infection that manifests in immunocompromised individuals
        distribution, and reproduction in any medium,   and  is  caused  by  the  varicella-zoster  virus  in  the  trigeminal  ganglion. The  condition  is
        provided the original work is properly cited.  characterized by severe pain and herpetic lesions, significantly impacting an individual’s
                                            quality of life and often triggering depression and anxiety [1]. The current guidelines for
                                            diagnosis and treatment [2] recommend conventional therapeutic approaches for herpes zoster,
                                            inclusive of antiviral agents combined with neurotrophic support, anti-inflammatory drugs,
                                            analgesics, and potential adjunctive physiotherapy in China [3]. While pulsed radiofrequency
                                            technology  has  been  extensively  studied  for  postherpetic  neuralgia,  the  approach  is
                                            challenged by the long duration of treatment, specific puncture positioning techniques,
                                            and  cumbersome  standardization  of  radiofrequency  parameters  [4-8].  Consequently,
                                            therapeutic outcomes of pulsed radiofrequency technology remain suboptimal. A pulsed
                                            microcurrent electrical neuromuscular stimulator (Figure 1) is a portable and wearable
                                            device that is commercially available and can function as an adjunctive treatment option.

                                                 DOI: https://doi.org/10.36922/jctr.23.00121
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