Page 52 - JCTR-11-3

Journal of Clinical and
Translational Research Greek propolis use in COVID-19: Trial protocol

43. Kubiliene L, Jekabsone A, Zilius M, et al. Comparison components analysis, antioxidant and antibacterial activity
of aqueous, polyethylene glycol-aqueous and ethanolic comparison. Food Sci Nutr. 2021;9(1):313-330.
propolis extracts: Antioxidant and mitochondria modulating doi: 10.1002/fsn3.1997
properties. BMC Complement Altern Med. 2018;18(1):165.
54. Elkhateeb OM, Badawy MEI, Noreldin AE, Abou-
doi: 10.1186/s12906-018-2234-5
Ahmed HM, El-Kammar MH, Elkhenany HA. Comparative
44. Sun C, Wu Z, Wang Z, Zhang H. Effect of ethanol/water evaluation of propolis nanostructured lipid carriers and its
solvents on phenolic profiles and antioxidant properties of crude extract for antioxidants, antimicrobial activity, and
beijing propolis extracts. Evid Based Complement Alternat skin regeneration potential. BMC Complement Med Ther.
Med. 2015;2015:595393. 2022;22(1):256.
doi: 10.1155/2015/595393 doi: 10.1186/s12906-022-03737-4
45. Kubiliene L, Laugaliene V, Pavilonis A, et al. Alternative 55. Yusof N, Abdul Munaim MS, Veloo Kutty R.
preparation of propolis extracts: comparison of their Ultrasound- assisted extraction propolis and its kinetic
composition and biological activities. BMC Complement study. IOP Conf Ser Mater Sci Eng. 2020;736(2):022089.
Altern Med. 2015;15(1):156.
doi: 10.1088/1757-899X/736/2/022089
doi: 10.1186/s12906-015-0677-5
56. Baysan U, Elmas F, Koç M. The effect of spray drying
46. Kara Y, Can Z, Kolaylı S. What should be the ideal solvent conditions on physicochemical properties of encapsulated
percentage and solvent-propolis ratio in the preparation propolis powder. J Food Process Eng. 2019;42(4):e13024.
of ethanolic propolis extract? Food Anal Methods.
2022;15(6):1707-1719. doi: 10.1111/jfpe.13024
doi: 10.1007/s12161-022-02244-z 57. Pant K, Thakur M, Chopra HK, Nanda V. Encapsulated
bee propolis powder: Drying process optimization and
47. Park YK, Ikegaki M. Preparation of water and ethanolic physicochemical characterization. LWT. 2022;155:112956.
extracts of propolis and evaluation of the preparations.
Biosci Biotechnol Biochem. 1998;62(11):2230-2232. doi: 10.1016/j.lwt.2021.112956
doi: 10.1271/bbb.62.2230 58. Asama T, Hiraoka T, Ohkuma A, Okumura N, Yamaki A,
Urakami K. Cognitive improvement and safety assessment of
48. Woisky RG, Salatino A. Analysis of propolis: Some a dietary supplement containing propolis extract in elderly
parameters and procedures for chemical quality control.
J Apic Res. 1998;37(2):99-105. Japanese: A placebo-controlled, randomized, parallel-group,
double-blind human clinical study. Evid Based Complement
doi: 10.1080/00218839.1998.11100961 Alternat Med. 2021;2021:6664217.
49. Graikou K, Popova M, Gortzi O, Bankova V, Chinou I. doi: 10.1155/2021/6664217
Characterization and biological evaluation of selected
Mediterranean propolis samples. Is it a new type? LWT. 59. Popova MP, Bankova VS, Bogdanov S, Tsvetkova I,
2016;65:261-267. Naydenski C, Marcazzan GL. Chemical characteristics
of poplar type propolis of different geographic origin.
doi: 10.1016/j.lwt.2015.08.025 Apidologie. 2007;38:306-311.
50. Aminimoghadamfarouj N, Nematollahi A. Propolis 60. Bankova V. Chemical diversity of propolis and the problem of
diterpenes as a remarkable bio-source for drug discovery standardization. J Ethnopharmacol. 2005;100(1-2):114-117.
development: A review. Int J Mol Sci. 2017;18(6):1290.
doi: 10.1016/j.jep.2005.05.004
doi: 10.3390/ijms18061290
61. Popova M, Bankova V, Butovska D, et al. Validated methods
51. Bankova V. Recent trends and important developments in for the quantification of biologically active constituents of
propolis research. Evid Based Complement Alternat Med. poplar‐type propolis. Phytochem Anal. 2004;15(4):235-240.
2005;2(1):29-32.
doi: 10.1002/pca.777
doi: 10.1093/ecam/neh059
62. Stefova M, Stafilov T, Kulevanova S. HPLC Analysis of
52. Oroian M, Ursachi F, Dranca F. Influence of ultrasonic Flavonoids. New York City: Marcel Dekker, Inc.; 2003.
amplitude, temperature, time and solvent concentration on p. 113-119.
bioactive compounds extraction from propolis. Ultrason
Sonochem. 2020;64:105021. 63. Asgharpour F, Moghadamnia AA, Kazemi S, Nouri HR,
Motallebnejad M. Applying GC-MS analysis to identify
doi: 10.1016/j.ultsonch.2020.105021 chemical composition of Iranian propolis prepared with
53. Ding Q, Sheikh AR, Gu X, et al. Chinese propolis: different solvent and evaluation of its biological activity.
Ultrasound‐assisted enhanced ethanolic extraction, volatile Caspian J Intern Med. 2020;11(2):191-198.

Volume 11 Issue 3 (2025) 46 doi: 10.36922/jctr.24.00073