Page 73 - JCTR-11-4

Journal of Clinical and
Translational Research Adherence and psoriasis severity in Brazil

Table 1. Sociodemographic characteristics of the participants Table 2. Clinical variants of psoriasis among participants

Characteristic n % Psoriasis variant n %
Sex Plaque 124 93.23
Male 71 53.38 Guttate 2 1.50
Female (non-pregnant) 58 43.61 Erythrodermic 2 1.50
Female (pregnant) 4 3.01 Plaque, inverse 2 1.50
Age Pustular 1 0.75
Adults* 80 60.15 Inverse 1 0.75
Elderly** 53 39.85 Plaque, pustular 1 0.75
Race or ethnicity
White 88 66.17 Table 3. Treatment adherence among participants
Mixed race 38 28.57
Treatment adherence n %
Black 7 5.26
High adherence 66 49.62
Marital status
Married 84 63.16 Moderate adherence 42 31.58
Moderate adherence 22 16.54
Legally married 18 13.53
Low adherence 3 2.26
Single 12 9.02
In a stable union for more than 6 months 12 9.02
Widowed 7 5.26 Table 4. Reasons for treatment discontinuation or
interruption among participants
Education level
Primary school 5 3.76 Reason n %
Junior high or middle school 4 3.01 Experienced discomfort or side effects 14 45.16
1 grade, elementary, or 1 grade equivalent 38 28.57 Perceived lack of treatment effectiveness 13 41.94
st
st
2 grade, high school, technical, normal, 57 42.86 Felt exhausted from continuous treatment 4 12.90
nd
scientific, or 2 grade equivalent Lost faith in psoriasis treatment 3 9.68
nd
Higher education or college degree 22 16.54 Uncertain about the reason 3 9.68
Postgraduate: specialization, master’s, doctorate 2 1.50 Financial constraints 2 6.45
Never studied 3 2.26
Did not know how to respond 2 1.50 Table 5. Dermatology life quality index of participants
Household income
Impact on quality of life n %
<1 minimum wage 2 1.50
No impact 64 48.12
1 minimum wage 25 18.80
Small impact 34 25.56
2 minimum wages 46 34.59
Moderate impact 12 9.02
3 minimum wages 22 16.54
Very large impact 18 13.53
4 minimum wages 19 14.29
Extremely large impact 5 3.76
5 – 10 minimum wages 12 9.02
Notes: * Indicates individuals aged 18 – 64; ** Indicates individuals
aged ≥65. impact” (13.53%), and “extremely large impact” (3.76%),
as detailed in Table 5.
reasons for treatment discontinuation included discomfort Figure 1 illustrates a negative correlation between PASI
and lack of belief in treatment effectiveness (Table 4). and treatment adherence, with a correlation coefficient
The DLQI results reveal that most participants perceived of −0.102 (rs² = 1.04%). Conversely, there was a positive
their skin condition as having little impact on their quality correlation between PASI and the history of treatment
of life. Nearly half (48.12%) reported “no impact“ at all, interruption (0.2444, rs² = 5.97%). This suggests that
and about a quarter (25.56%) experienced only a “small 1.04% of the PASI variation may be attributed to treatment
impact.” A smaller proportion reported more noticeable adherence failure, while 5.97% may be related to the history
effects such as “moderate impact” (9.02%), “very large of treatment interruptions.

Volume 11 Issue 4 (2025) 67 doi: 10.36922/jctr.24.00057