Page 108 - MI-2-1

Microbes & Immunity Advax-adjuvanted typhoid vaccine

adjuvanted severe acute respiratory syndrome coronavirus implications after vaccination with polysaccharide
2 spike protein vaccine: A phase 3 randomized placebo- or glycoconjugate vaccines. Expert Rev Vaccines.
controlled trial. Clin Microbiol Infect. 2023;29:215-220. 2011;10:307-322.
doi: 10.1016/j.cmi.2022.09.001 doi: 10.1586/erv.11.8
43. Tabarsi P, Anjidani N, Shahpari R, et al. Safety and 49. Keitel WA, Bond NL, Zahradnik JM, Cramton TA,
immunogenicity of SpikoGen(R), an Advax‑CpG55.2‑ Robbins JB. Clinical and serological responses following
adjuvanted SARS‑CoV‑2 spike protein vaccine: A phase 2 primary and booster immunization with Salmonella typhi Vi
randomized placebo-controlled trial in both seropositive capsular polysaccharide vaccines. Vaccine. 1994;12:195-199.
and seronegative populations. Clin Microbiol Infect. doi: 10.1016/0264-410x(94)90194-5
2022;28:1263-1271.
50. Yang JS, Kim HJ, Yun CH, et al. A semi-automated
doi: 10.1016/j.cmi.2022.04.004 vibriocidal assay for improved measurement of cholera
44. Tabarsi P, Anjidani N, Shahpari R, et al. Immunogenicity vaccine-induced immune responses. J Microbiol Methods.
and safety of SpikoGen(R), an adjuvanted recombinant 2007;71:141-146.
SARS‑CoV‑2 spike protein vaccine as a homologous and doi: 10.1016/j.mimet.2007.08.009
heterologous booster vaccination: A randomized placebo-
controlled trial. Immunology. 2022;167:340-353. 51. Maslanka SE, Gheesling LL, Libutti DE, et al. Standardization
and a multilaboratory comparison of Neisseria meningitidis
doi: 10.1111/imm.13540 serogroup A and C serum bactericidal assays. The
45. Sakala IG, Eichinger KM, Petrovsky N. Neonatal vaccine Multilaboratory Study Group. Clin Diagn Lab Immunol.
effectiveness and the role of adjuvants. Expert Rev Clin 1997;4:156-167.
Immunol. 2019;15:869-878. doi: 10.1128/cdli.4.2.156-167.1997
doi: 10.1080/1744666X.2019.1642748 52. Pulickal AS, Gautam S, Clutterbuck EA, et al. Kinetics of the
46. Honda‑Okubo Y, Ong CH, Petrovsky N. Advax delta inulin natural, humoral immune response to Salmonella enterica
adjuvant overcomes immune immaturity in neonatal mice serovar Typhi in Kathmandu, Nepal. Clin Vaccine Immunol.
thereby allowing single-dose influenza vaccine protection. 2009;16:1413-1419.
Vaccine. 2015;33:4892-4900. doi: 10.1128/CVI.00245‑09
doi: 10.1016/j.vaccine.2015.07.051 53. Feasey NA, Levine MM. Typhoid vaccine development with
47. Sakala IG, Honda‑Okubo Y, Li L, Baldwin J, Petrovsky N. a human challenge model. Lancet. 2017;390:2419-2421.
A M2 protein‑based universal influenza vaccine containing doi: 10.1016/S0140-6736(17)32407-8
Advax‑SM adjuvant provides newborn protection 54. Waddington CS, Darton TC, Woodward WE, Angus B,
via maternal or neonatal immunization. Vaccine. Levine MM, Pollard AJ. Advancing the management and
2021;39:5162-5172.
control of typhoid fever: A review of the historical role of
doi: 10.1016/j.vaccine.2021.07.037 human challenge studies. J Infect. 2014;68:405-418.
48. Poolman J, Borrow R. Hyporesponsiveness and its clinical doi: 10.1016/j.jinf.2014.01.006

Volume 2 Issue 1 (2025) 100 doi: 10.36922/mi.4497