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Microbes & Immunity Copper and cuproptosis in immunity
thorough studies of cuproptosis and its associated genes on mechanical properties of biocompatible Ti-mo alloys:
necessitate well-designed pre-clinical experiments and A simulation-based investigation. Micromachines (Basel).
clinical trials, which present significant implementation 2023;14(5):1081.
challenges. Nonetheless, this is a promising research area, doi: 10.3390/mi14051081
and we look forward to future advancements.
4. Huang X, Li Q, Yun S, et al. Zn(II) enhances the antimicrobial
Acknowledgments effect of chloroxine and structural analogues against drug-
resistant ESKAPE pathogens in vitro. Biochem Pharmacol.
None. 2024;229:116482.
Funding doi: 10.1016/j.bcp.2024.116482
5. Hager S, Korbula K, Bielec B, et al. The thiosemicarbazone
This work was supported by the Chongqing Postdoctoral Me NNMe induces paraptosis by disrupting the ER thiol
Science Foundation (7820100597) and the Natural Science redox homeostasis based on protein disulfide isomerase
2
2
Foundation (grant numbers: 82072246, 82211530059). inhibition. Cell Death Dis. 2018;9(11):1052.
Conflict of interest doi: 10.1038/s41419-018-1102-z
Jianping Xie is the Editorial Board Member of this journal 6. Wang M, Huang H, Ma X, Huang C, Peng X. Copper metal-
but was not in any way involved in the editorial and organic framework embedded carboxymethyl chitosan-g-
glutathione/polyacrylamide hydrogels for killing bacteria
peer-review process conducted for this paper, directly or and promoting wound healing. Int J Biol Macromol.
indirectly. Separately, other authors declared that they 2021;187:699-709.
have no known competing financial interests or personal
relationships that could have influenced the work reported doi: 10.1016/j.ijbiomac.2021.07.139
in this paper. 7. Culbertson EM, Culotta VC. Copper in infectious disease:
Using both sides of the penny. Semin Cell Dev Biol.
Author contributions 2021;115:19-26.
Conceptualization: All authors doi: 10.1016/j.semcdb.2020.12.003
Visualization: Junqi Xu 8. Gao L, Zhang A. Copper-instigated modulatory cell
Writing–original draft: All authors mortality mechanisms and progress in oncological treatment
Writing–review & editing: All authors investigations. Front Immunol. 2023;14:1236063.
Ethics approval and consent to participate doi: 10.3389/fimmu.2023.1236063
Not applicable. 9. Zuhra K, Panagaki T, Randi EB, et al. Mechanism of
cystathionine-beta-synthase inhibition by disulfiram:
Consent for publication The role of bis(N,N-diethyldithiocarbamate)-copper(II).
Biochem Pharmacol. 2020;182:114267.
Not applicable.
doi: 10.1016/j.bcp.2020.114267
Availability of data 10. May KL, Lehman KM, Mitchell AM, Grabowicz M. A stress
response monitoring lipoprotein trafficking to the outer
Not applicable. membrane. mBio. 2019;10(3):e00618-19.
References doi: 10.1128/mBio.00618-19
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Bodaghi M, Rezayat M. Influence of aluminum and copper by synergistic chemodynamic and cuproptosis therapy.
Volume 2 Issue 1 (2025) 66 doi: 10.36922/mi.5657

