Page 35 - MI-2-3
P. 35
Microbes & Immunity Correlation between VZV and cancer
36. Sebastian AP, Basu A, Mitta N, Benjamin D. Transverse differential expression of pro- and antiapoptosis genes by
myelitis caused by varicella-zoster. BMJ Case varicella-zoster virus-infected neurons and fibroblasts.
Rep. 2021;14(8):e243217. J Virol. 2014;88(13):7674-7677.
doi: 10.1136/bcr-2020-238078 doi: 10.1128/JVI.00500-14
37. Mirouse A, Vignon P, Piron P, et al. Severe varicella-zoster 48. Wong RS. Apoptosis in cancer: From pathogenesis to
virus pneumonia: A multicenter cohort study. Crit Care. treatment. J Exp Clin Cancer Res. 2011;30(1):87.
2017;21(1):137.
doi: 10.1186/1756-9966-30-87
doi: 10.1186/s13054-017-1731-0
49. Chen X, Duan N, Zhang C, Zhang W. Survivin and
38. Cao LJ, Zheng YM, Li F, Hao HJ, Gao F. Varicella-zoster tumorigenesis: Molecular mechanisms and therapeutic
virus meningitis with hypoglycorrhachia: A case report. strategies. J Cancer. 2016;7(3):314-323.
World J Clin Cases. 2023;11(29):7101-7106.
doi: 10.7150/jca.13332
doi: 10.12998/wjcc.v11.i29.7101
50. Ge J, Wang Y, Li X, et al. Phosphorylation of caspases by
39. Eleftheriou D, Moraitis E, Hong Y, et al. Microparticle- a bacterial kinase inhibits host programmed cell death. Nat
mediated VZV propagation and endothelial activation: Commun. 2024;15(1):8464.
Mechanism of VZV vasculopathy. Neurology.
2020;94(5):e474-e480. doi: 10.1038/s41467-024-52817-1
51. Albadari N, Li W. Survivin small molecules inhibitors:
doi: 10.1212/WNL.0000000000008885
Recent advances and challenges. Molecules. 2023;28(3):1376.
40. Hertzog J, Zhou W, Fowler G, et al. Varicella-Zoster virus
ORF9 is an antagonist of the DNA sensor cGAS. EMBO J. doi: 10.3390/molecules28031376
2022;41(14):e109217. 52. Warrier NM, Agarwal P, Kumar P. Emerging importance of
doi: 10.15252/embj.2021109217 survivin in stem cells and cancer: The development of new
cancer therapeutics. Stem Cell Rev Rep. 2020;16(5):828-852.
41. Zahid A, Ismail H, Li B, Jin T. Molecular and structural
basis of DNA sensors in antiviral innate immunity. Front doi: 10.1007/s12015-020-09995-4
Immunol. 2020;11:613039. 53. Aggarwal D, Shetty DC, Jain A, Gulati N, Juneja S.
doi: 10.3389/fimmu.2020.613039 Pathogenetic model of survivin-dependent molecular
signalling pathways in tumorigenesis of oral cancer and
42. Liu H, Zhang H, Wu X, et al. Nuclear cGAS suppresses precursor lesions. J Oral Maxillofac Pathol. 2023;27(2):
DNA repair and promotes tumorigenesis. Nature. 287-294.
2018;563(7729):131-136.
doi: 10.4103/jomfp.jomfp_5_23
doi: 10.1038/s41586-018-0629-6
54. Liu T, Brouha B, Grossman D. Rapid induction of
43. Du JM, Qian MJ, Yuan T, et al. cGAS and cancer therapy: mitochondrial events and caspase-independent apoptosis
A double-edged sword. Acta Pharmacol Sin. 2022;43(9): in Survivin-targeted melanoma cells. Oncogene. 2004;23(1):
2202-2211. 39-48.
doi: 10.1038/s41401-021-00839-6 doi: 10.1038/sj.onc.1206978
44. Nguyen LN, Kanneganti TD. PANoptosis in viral infection: 55. Moffat JF, Greenblatt RJ. Effects of varicella-zoster virus on
The missing puzzle piece in the cell death field. J Mol Biol. cell cycle regulatory pathways. Curr Top Microbiol Immunol.
2022;434(4):167249. 2010;342:67-77.
doi: 10.1016/j.jmb.2021.167249 doi: 10.1007/82_2010_28
45. Kennedy PG, Graner MW, Gunaydin D, Bowlin J, Pointon T, 56. Kovalishyn V, Severin O, Kachaeva M, et al. In silico design
Yu X. Varicella-Zoster Virus infected human neurons are and experimental validation of novel oxazole derivatives
resistant to apoptosis. J Neurovirol. 2020;26(3):330-337. against varicella zoster virus. Mol Biotechnol. 2024;66(4):
doi: 10.1007/s13365-020-00831-6 707-717.
46. Steain M, Slobedman B, Abendroth A. Modulation of doi: 10.1007/s12033-023-00670-w
apoptosis and cell death pathways by varicella-zoster virus. 57. Traves R, Opadchy T, Slobedman B, Abendroth A. Varicella
Curr Top Microbiol Immunol. 2023;438:59-73.
zoster virus downregulates expression of the nonclassical
doi: 10.1007/82_2021_249 antigen presentation molecule CD1d. J Infect Dis.
2024;230(2):e416-e426.
47. Markus A, Waldman Ben-Asher H, Kinchington PR,
Goldstein RS. Cellular transcriptome analysis reveals doi: 10.1093/infdis/jiad512
Volume 2 Issue 3 (2025) 27 doi: 10.36922/mi.8320

