Page 18 - MI-2-4

Microbes & Immunity Regulation of Staphylococcus aureus CP biosynthesis

Funding 3. Chen XW, Chen HQ, Wu JH, et al. Isoniazid potentiates
tigecycline to kill methicillin-resistant Staphylococcus
The study was supported by the National Natural Science aureus. Emerg Microbes Infect. 2025;14(1):2434587.
Foundation of China (Grant no. 82272341 for Xiancai
Rao; Grant no. 82472301 for Yifan Rao) and Category doi: 10.1080/22221751.2024.2434587
II Academic Excellence Program of Xinqiao Hospital of 4. Dang X, Han S, Du Y, Fei Y, Guo B, Wang X. Engineered
Army Medical University (Grant no. 2023XKRC019 for environment-friendly multifunctional food packaging
Yifan Rao). The funders had no role in study design, data with superior nonleachability, polymer miscibility and
collection, interpretation, or the decision to submit the antimicrobial activity. Food Chem. 2025;466:142192.
work for publication. doi: 10.1016/j.foodchem.2024.142192
5. DeLeo FR, Chambers HF. Reemergence of antibiotic-
Conflict of interest resistant Staphylococcus aureus in the genomics era. J Clin

Xiancai Rao is an Editorial Board Member of this journal Invest. 2009;119(9):2464-2474.
but was not in any way involved in the editorial and doi: 10.1172/JCI38226
peer-review process conducted for this paper, directly or 6. Gordon RJ, Lowy FD. Pathogenesis of methicillin-
indirectly. Separately, other authors declared that they resistant Staphylococcus aureus infection. Clin Infect Dis.
have no known competing financial interests or personal 2008;46(Suppl 5):S350-S359.
relationships that could have influenced the work reported doi: 10.1086/533591
in this paper.
7. Nguyen TH, Cheung G, Rigby KM, et al. Rapid pathogen-
Author contributions specific recruitment of immune effector cells in the skin by
secreted toxins. Nat Microbiol. 2022;7(1):62-72.
Conceptualization: Xiancai Rao, Guixue Wang
Visualization: Yifan Rao, Huagang Peng doi: 10.1038/s41564-021-01012-9
Writing–original draft: Yifan Rao, Zuwen Guo, Huagang 8. Chakraborty T, Polley S, Ray Chaudhuri N, et al.
Peng A staphylococcal capsule-producing enzyme that unfolds via
Writing–review & editing: Yifan Rao, Xiancai Rao, Guixue multiple intermediates predominantly exists as the trimers at
Wang low concentrations. J Biomol Struct Dyn. 2024;1-15.
Ethics approval and consent to participate doi: 10.1080/07391102.2024.2438364
9. Gilbert I. Dissociation in an encapsulated Staphylococcus.
Not applicable.
J Bacteriol. 1931;21(3):157-160.
Consent for publication doi: 10.1128/jb.21.3.157-160.1931
Not applicable. 10. Sompolinsky D, Samra Z, Karakawa WW, Vann WF,
Schneerson R, Malik Z. Encapsulation and capsular
Availability of data types in isolates of Staphylococcus aureus from different
sources and relationship to phage types. J Clin Microbiol.
Not applicable. 1985;22(5):828-834.
References doi: 10.1128/jcm.22.5.828-834.1985
1. Eltabeeb MA, Hamed RR, El-Nabarawi MA, et al. 11. Visansirikul S, Kolodziej SA, Demchenko AV. Staphylococcus
Nanocomposite alginate hydrogel loaded with propranolol aureus capsular polysaccharides: A structural and synthetic
hydrochloride kolliphor-based cerosomes as a repurposed perspective. Org Biomol Chem. 2020;18(5):783-798.
platform for methicillin-resistant Staphylococcus aureus- doi: 10.1039/c9ob02546d
(MRSA)-induced skin infection; in-vitro, ex-vivo,
in-silico, and in-vivo evaluation. Drug Deliv Transl Res. 12. Keinhörster D, George SE, Weidenmaier C, Wolz C.
2025;15(2):556-576. Function and regulation of Staphylococcus aureus wall
teichoic acids and capsular polysaccharides. Int J Med
doi: 10.1007/s13346-024-01611-z Microbiol. 2019;309(6):151333.
2. Li L, Koirala B, Hernandez Y, et al. Identification of doi: 10.1016/j.ijmm.2019.151333
structurally diverse menaquinone-binding antibiotics with
in vivo activity against multidrug-resistant pathogens. Nat 13. Tuchscherr L, Löffler B, Buzzola FR, Sordelli DO.
Staphylococcus aureus adaptation to the host and persistence:
Microbiol. 2022;7(1):120-131.
Role of loss of capsular polysaccharide expression. Future
doi: 10.1038/s41564-021-01013-8 Microbiol. 2010;5(12):1823-1832.

Volume 2 Issue 4 (2025) 10 doi: 10.36922/mi.8392