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Microbes & Immunity Brachyspira pilosicoli novel outer membrane proteins

Table 3. Sequence variations among nine strains: Total variations and variations in the extracellular loops of predicted outer
membrane β-barrel proteins
Locus identifier Protein names a Total variations Variations present on the predicted
extracellular loop region
Group A
BP951000_RS05730 OMP assembly factor BamA Six variations: D60, A184, V465, A467, None
and F512
BP951000_RS10215 b Variable surface protein (VspE) 208 variations Not determined c
BP951000_RS04760 b Variable surface protein (VspD) 260 variations Not determined c
BP951000_RS01125 CsgG/HfaB family protein Five variations: S63, D79, T190, I210, None
and L380
BP951000_RS03440 OMBB protein Six variations: F24, V47, V64, N110, V47
D169, and A197
BP951000_RS05600 TolC family protein Two variations: T246 and N499 None
BP951000_RS09000 TolC family protein Two variations: S90 and S131 S90
BP951000_RS06235 TolC family protein 18 variations: K2, N3, F5, V6, F7, I8, I10, L93
L12, S16, S25, N33, I42, E43, L93, S105,
E136, I137, and T210
BP951000_RS04880 Serpentine receptor domain- One variation: N69 None
containing protein
BP951000_RS02055 Serpentine receptor domain- Three variations: H101, N163 and M235 N163 and M235
containing protein
BP951000_RS02050 Serpentine receptor domain- Five variations: A27, L28, T108, A228, T108 and A228
containing protein and I247
BP951000_RS07540 Serpentine receptor domain- Six variations: M1, K2, K3, I4, I5, and L6 None
containing protein
BP951000_RS00180 Serpentine receptor domain- Two variations: I64 and M115 None
containing protein
Group B
BP951000_RS09575 Lipopolysaccharide-assembly Seven variations: N14, G137, I257, I382, D600
protein (LptD) E454, D600, and G944
BP951000_RS03215 b TonB-dependent siderophore 59 variations Not determined c
receptor
BP951000_RS04405 Toxin A 23 variations: M1, H2, R3, I4, I6, L8, T9, N41, F84, K90, N98, S175, and Q183
M18, V19, T24, N32, S34, N41, F84, K90,
N98, I101, S102, N104, S175, Q183, I264,
and T303
BP951000_RS09655 b DUF5723 domain-containing 315 variations Not determined c
protein
BP951000_RS04440 Hypothetical protein 13 variations: K104, K113, S117, Y124, K104 and L243
I132, T134, N151, G153, L243, V252,
L254, S308, N321
BP951000_RS08285 b Trep protein 43 variations Not determined c
BP951000_RS04505 b Variable surface protein (VspH) 247 variations Not determined c
BP951000_RS08455 PorV/PorQ family protein Six variations: L12, S20, N22, A117, N22 and A117
R187, and S253
BP951000_RS01090 Variable surface protein (VspH) One variation: E258 E258
BP951000_RS06935 Hypothetical protein Four variations: S9, I10, V13, and R298 None
BP951000_RS11380 Toxin A Three variations: M126, M154, and I278 M126
(Cont'd...)

Volume 2 Issue 4 (2025) 88 doi: 10.36922/MI025230050