Page 48 - OR-1-2

Principles, progress, and projections. Cold Spring Harb Science. 2010;330:774-778.
Perspect Biol. 2012;4:a008300.
doi: 10.1126/science.1190928
doi: 10.1101/cshperspect.a008300
132. Aisenbrey EA, Murphy WL. Synthetic alternatives to
120. Young MD, Mitchell TJ, Vieira Braga FA, et al. Single-cell matrigel. Nat Rev Mater. 2020;5:539-551.
transcriptomes from human kidneys reveal the cellular
identity of renal tumors. Science. 2018;361:594-599. doi: 10.1038/s41578-020-0199-8
133. Chooi WH, Ng CY, Ow V, et al. Defined alginate hydrogels
doi: 10.1126/science.aat1699
support spinal cord organoid derivation, maturation,
121. Nam SA, Seo E, Kim JW, et al. Graft immaturity and safety and modeling of spinal cord diseases. Adv Healthc Mater.
concerns in transplanted human kidney organoids. Exp Mol 2023;12:e2202342.
Med. 2019;51:1-13.
doi: 10.1002/adhm.202202342
doi: 10.1038/s12276-019-0336-x
134. Wang Z, Liu R, Liu Y, et al. Human placenta decellularized
122. Nerger BA, Sinha S, Lee NN, et al. 3D hydrogel encapsulation extracellular matrix hydrogel promotes the generation of
regulates nephrogenesis in kidney organoids. Adv Mater. human spinal cord organoids with dorsoventral organization
2024;36:e2308325. from human induced pluripotent stem cells. ACS Biomater
doi: 10.1002/adma.202308325 Sci Eng. 2024;10:3218-3231.
123. Garreta E, Moya-Rull D, Marco A, et al. Natural hydrogels doi: 10.1021/acsbiomaterials.4c00067
support kidney organoid generation and promote in vitro 135. Olsen BR, Reginato AM, Wang W. Bone development. Annu
angiogenesis. Adv Mater. 2024;36:e2400306. Rev Cell Dev Biol. 2000;16:191-220.
doi: 10.1002/adma.202400306 doi: 10.1146/annurev.cellbio.16.1.191.2000
124. Lenroot RK, Giedd JN. Brain development in children and 136. Filipowska J, Tomaszewski KA, Niedźwiedzki Ł, Walocha JA,
adolescents: Insights from anatomical magnetic resonance Niedźwiedzki T. The role of vasculature in bone development,
imaging. Neurosci Biobehav Rev. 2006;30:718-729. regeneration and proper systemic functioning. Angiogenesis.
doi: 10.1016/j.neubiorev.2006.06.001 2017;20:291-302.
125. Collin G, Van Den Heuvel MP. The ontogeny of the human doi: 10.1007/s10456-017-9541-1
connectome: Development and dynamic changes of brain 137. Kronenberg HM. Developmental regulation of the growth
connectivity across the life span. Neuroscientist. 2013;19:616-628.
plate. Nature. 2003;423:332-336.
doi: 10.1177/1073858413503712
doi: 10.1038/nature01657
126. Mattei D, Pietrobelli A. Micronutrients and brain 138. Zhao D, Saiding Q, Li Y, Tang Y, Cui W. Bone organoids:
development. Curr Nutr Rep. 2019;8:99-107.
Recent advances and future challenges. Adv Healthc Mater.
doi: 10.1007/s13668-019-0268-z 2023;13:e2302088.
127. Kalia M. Brain development: Anatomy, connectivity, adaptive doi: 10.1002/adhm.202302088
plasticity, and toxicity. Metabolism. 2008;57:S2-S5.
139. Lin Z, Zhao Y, Chu PK, et al. A functionalized TiO2/
doi: 10.1016/j.metabol.2008.07.009 Mg2TiO4 nano-layer on biodegradable magnesium implant
128. Isik M, Okesola BO, Eylem CC, et al. Bioactive and chemically enables superior bone-implant integration and bacterial
defined hydrogels with tunable stiffness guide cerebral disinfection. Biomaterials. 2019;219:119372.
organoid formation and modulate multi-omics plasticity in doi: 10.1016/j.biomaterials.2019.119372
cerebral organoids. Acta Biomater. 2023;171:223-238.
140. Lee J, Lee S, Ahmad T, et al. Human adipose-derived stem
doi: 10.1016/j.actbio.2023.09.040 cell spheroids incorporating platelet-derived growth factor
129. Cho AN, Jin Y, An Y, et al. Microfluidic device with brain (PDGF) and bio-minerals for vascularized bone tissue
extracellular matrix promotes structural and functional engineering. Biomaterials. 2020;255:120192.
maturation of human brain organoids. Nat Commun. doi: 10.1016/j.biomaterials.2020.120192
2021;12:4730.
141. Xie C, Liang R, Ye J, et al. High-efficient engineering of
doi: 10.1038/s41467-021-24775-5 osteo-callus organoids for rapid bone regeneration within
130. Welniarz Q, Dusart I, Roze E. The corticospinal tract: one month. Biomaterials. 2022;288:121741.
Evolution, development, and human disorders. Dev doi: 10.1016/j.biomaterials.2022.121741
Neurobiol. 2017;77:810-829.
142. Wang J, Wu Y, Li G, et al. Engineering large-scale self-
doi: 10.1002/dneu.22455
mineralizing bone organoids with bone matrix-inspired
131. Freeman MR. Specification and morphogenesis of astrocytes. hydroxyapatite hybrid bioinks. Adv Mater. 2024;36:e2309875.

Volume 1 Issue 2 (2025) 27 doi: 10.36922/or.8262