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A

B

C

Figure 9. Vascularized brain organoids for disease modeling. (A) Alzheimer’s disease model. 122,181 Copyright © 2019, Authors. Copyright © 2023,
208
183
Authors. (B) Ischemic stroke model. Copyright © 2020, Authors. (C) Glioblastoma multiforme model. Reproduced from Xiao et al. Copyright ©
2019, Authors.
Abbreviations: AD: Alzheimer’s disease; bEC: Brain endothelial cells; DMSO: Dimethyl sulfoxide; GBM: Glioblastomas; IgG: Immunoglobulin G; ReN:
Human neural progenitor cells; WT: Wild-type; Zo-1: Zona-occluden 1; 3D: Three-dimensional.

Volume 1 Issue 2 (2025) 22 doi: 10.36922/or.8162