Page 25 - OR-1-3

53. Abdollahiyan P, Oroojalian F, Mokhtarzadeh A, doi: 10.1038/s41467-023-36408-0
de la Guardia M. Hydrogel-based 3D bioprinting 64. Xie C, Liang R, Ye J, et al. High-efficient engineering of
for bone and cartilage tissue engineering. Biotechnol osteo-callus organoids for rapid bone regeneration within
J. 2020;15(12):e2000095.
one month. Biomaterials. 2022;288:121741.
doi: 10.1002/biot.202000095
doi: 10.1016/j.biomaterials.2022.121741
54. Shen C, Wang J, Li G, et al. Boosting cartilage repair with silk
fibroin-DNA hydrogel-based cartilage organoid precursor. 65. Lin X, Patil S, Gao YG, Qian A. The Bone extracellular matrix
Bioact Mater. 2024;35:429-444. in bone formation and regeneration. Front Pharmacol.
2020;11:757.
doi: 10.1016/j.bioactmat.2024.02.016
doi: 10.3389/fphar.2020.00757
55. Wu S, Wu X, Wang X, Su J. Hydrogels for bone organoid
construction: From a materiobiological perspective. J Mater 66. Lamandé SR, Ng ES, Cameron TL, et al. Modeling human
Sci Technol. 2023;136(0):21-31. skeletal development using human pluripotent stem cells.
Proc Natl Acad Sci U S A. 2023;120(19):e2211510120.
doi: 10.1016/j.jmst.2022.07.008
doi: 10.1073/pnas.2211510120
56. Zhu T, Hu Y, Cui H, Cui H. 3D Multispheroid assembly
strategies towards tissue engineering and disease modeling. 67. Eiraku M, Takata N, Ishibashi H, et al. Self-organizing optic-
Adv Healthc Mater. 2024;13:e2400957. cup morphogenesis in three-dimensional culture. Nature.
2011;472(7341):51-56.
doi: 10.1002/adhm.202400957
doi: 10.1038/nature09941
57. Rausch M, Iqbal N, Pathak S, Owston HE, Ganguly P.
Organoid models and next-generation sequencing for bone 68. Boj SF, Hwang CI, Baker LA, et al. Organoid models
marrow and related disorders. Organoids. 2023;2(3):123-139. of human and mouse ductal pancreatic cancer. Cell.
2015;160(1-2):324-338.
doi: 10.3390/organoids2030010
doi: 10.1016/j.cell.2014.12.021
58. Augello A, De Bari C. The regulation of differentiation
in mesenchymal stem cells. Hum Gene Ther. 2010; 69. Takebe T, Sekine K, Enomura M, et al. Vascularized and
21(10):1226-1238. functional human liver from an iPSC-derived organ bud
transplant. Nature. 2013;499(7459):481-484.
doi: 10.1089/hum.2010.173
doi: 10.1038/nature12271
59. León IE, Cadavid-Vargas JF, Resasco A, et al. In vitro and
in vivo antitumor effects of the VO-chrysin complex 70. Sun Y, You Y, Wu Q, Hu R, Dai K. Senescence-targeted
on a new three-dimensional osteosarcoma spheroids MicroRNA/Organoid composite hydrogel repair cartilage
model and a xenograft tumor in mice. J Biol Inorg Chem. defect and prevention joint degeneration via improved
2016;21(8):1009-1020. chondrocyte homeostasis. Bioact Mater. 2024;39:427-442.
doi: 10.1007/s00775-016-1397-0 doi: 10.1016/j.bioactmat.2024.05.036
60. Visconti RJ, Kolaja K, Cottrell JA. A functional three- 71. Cheng A, Schwartz Z, Kahn A, et al. Advances in porous
dimensional microphysiological human model of myeloma scaffold design for bone and cartilage tissue engineering and
bone disease. J Bone Miner Res. 2021;36(10):1914-1930. regeneration. Tissue Eng Part B Rev. 2019;25(1):14-29.
doi: 10.1002/jbmr.4404 doi: 10.1089/ten.TEB.2018.0119
61. Cullier A, Cassé F, Manivong S, et al. Functionalized nanogels 72. Qasim M, Chae DS, Lee NY. Advancements and frontiers in
with endothelin-1 and bradykinin receptor antagonist nano-based 3D and 4D scaffolds for bone and cartilage tissue
peptides decrease inflammatory and cartilage degradation engineering. Int J Nanomedicine. 2019;14:4333-4351.
markers of osteoarthritis in a horse organoid model of doi: 10.2147/IJN.S209431
cartilage. Int J Mol Sci. 2022;23(16):8949.
73. Liu X, Jin X, Ma PX. Nanofibrous hollow microspheres
doi: 10.3390/ijms23168949 self-assembled from star-shaped polymers as injectable cell
62. Kleuskens MWA, Crispim JF, van Donkelaar CC, carriers for knee repair. Nat Mater. 2011;10(5):398-406.
Janssen RPA, Ito K. Evaluating initial integration of cell- doi: 10.1038/nmat2999
based chondrogenic constructs in human osteochondral
explants. Tissue Eng Part C Methods. 2022;28(1):34-44. 74. Sun Y, Ding Q. Genome engineering of stem cell organoids
for disease modeling. Protein Cell. 2017;8(5):315-327.
doi: 10.1089/ten.TEC.2021.0196
doi: 10.1007/s13238-016-0368-0
63. Abe K, Yamashita A, Morioka M, et al. Engraftment
of allogeneic iPS cell-derived cartilage organoid in a 75. Paggi CA, Teixeira LM, Le Gac S, Karperien M. Joint-on-chip
primate model of articular cartilage defect. Nat Commun. platforms: Entering a new era of in vitro models for arthritis.
2023;14(1):804. Nat Rev Rheumatol. 2022;18(4):217-231.

Volume 1 Issue 3 (2025) 16 doi: 10.36922/or.8295