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Tumor Discovery                                                   Choroid plexus tumors: Benign to malignant



            5. Conclusion                                         https://doi.org/10.1007/s00401-009-0627-8

            CPTs can be difficult to distinguish due to the similar   2.   Gopal P, Parker JR, Debski R, et al., 2008, Choroid plexus
            pathophysiology shared by the tumor subtypes, which   carcinoma. Arch Pathol Lab Med, 132(8): 1350–1354.
            result in overlapping manifestations. However, CPT      https://doi.org/10.5858/2008-132-1350-CPC
            subtypes can be clearly differentiated from each other by   3.   Wolff JEA, Sajedi M, Brant R, et al., 2002, Choroid plexus
            detecting differences in histology, immunohistochemistry,   tumours. Br J Cancer, 87(10): 1086–1091.
            imaging, gross appearance, location, metastatic behavior,
            treatment approach, and prognosis. Therefore, a better      https://doi.org/10.1038/sj.bjc.6600609
            understanding of these differences can aid in exploring   4.   Ruiz-Garcia H, Huayllani MT,  Incontri D,  et al., 2020,
            future treatments for CPTs. Emerging treatments for CPTs   Intraventricular  choroid  plexus  tumors:  Clinical
            include neuroendoscopy, LITT, PTT, immunotherapy,     characteristics and impact of current management on
            manipulation of the TME, gene therapy, epigenetic     survival. J Neurooncol, 149(2): 283–292.
            modulators, and nanotechnology. However, CPTs mainly      https://doi.org/10.1007/s11060-020-03603-8
            affect pediatric patients, often presenting as small, highly   5.   Jaiswal S, Vij M, Mehrotra A, et al., 2013, Choroid plexus
            vascularized tumors. These factors, in addition to their   tumors: A clinico-pathological and neuro-radiological study
            relatively lower incidence rate, complicate their management   of 23 cases. Asian J Neurosurg, 8(1): 29–35.
            using conventional techniques as well as novel treatments,      https://doi.org/10.4103/1793-5482.110277
            many of which are primarily focused on more common
            brain tumors. Further investigation is warranted to establish   6.   Hasselblatt M, Böhm C, Tatenhorst L,  et al., 2006,
            a standard treatment approach for each CPT subtype and   Identification of novel diagnostic markers for choroid
            the applicability and efficacy of emerging treatments.  plexus  tumors:  A  microarray-based  approach.  Am J Surg
                                                                  Pathol, 30(1): 66–74.
            Acknowledgments                                       https://doi.org/10.1097/01.PAS.0000176430.88702.E0
            None.                                              7.   Raimondi AJ, Gutierrez FA, 1975, Diagnosis and surgical
                                                                  treatment of choroid plexus papillomas. Pediatr Neurosurg,
            Funding                                               1(2–3): 81–115.
            None.                                                 https://doi.org/10.1159/000119558

            Conflict of interest                               8.   Zhou WJL, Wang X, Peng JY, et al., 2018, Clinical features
                                                                  and prognostic risk factors of choroid plexus tumors in
            The authors declare that they have no competing interests.  children. Chin Med J (Engl), 131(24): 2938–2946.
                                                                  https://doi.org/10.4103/0366-6999.247195
            Author contributions
                                                               9.   Prendergast N, Goldstein JD, Beier AD, 2018, Choroid
            Conceptualization: Brandon Lucke-Wold, Phillip M.     plexus adenoma in a child: Expanding the clinical and
               Johansen                                           pathological spectrum. J Neurosurg Pediatr, 21(4): 428–433.
            Writing – original draft: All authors                 https://doi.org/10.3171/2017.10.PEDS17290
            Writing – review & editing: Ali A. Mohamed, Thomas
               Caussat, Phillip M. Johansen, Brandon Lucke-Wold  10.  Ajir F, Chanbusarakum K, Craig Bolles J, 1982, Acinar
                                                                  choroid plexus adenoma of the fourth ventricle. Surg Neurol,
            Ethics approval and consent to participate            17(4): 290–292.
            Not applicable.                                       https://doi.org/10.1016/0090-3019(82)90125-2
                                                               11.  Andreini L, Doglioni C, Giangaspero F, 1991, Tubular
            Consent for publication                               adenoma of choroid plexus: A case report. Clin Neuropathol,
            Not applicable.                                       10(3): 137–140.
                                                               12.  Duckett S, Osterholm J, Schaefer D,  et al., 1991, Ossified
            Availability of data                                  mucin-secreting choroid plexus adenoma: Case report.
                                                                  Neurosurgery, 29(1): 130–132.
            Not applicable.
                                                                  https://doi.org/10.1227/00006123-199107000-00024
            References
                                                               13.  Eljamel MSM, Jeffreys RV, 1990, Mucous-secreting choroid
            1.   Wolburg H, Paulus W, 2010, Choroid plexus: Biology and   plexus adenoma - case report and review of the literature.
               pathology. Acta Neuropathol, 119(1): 75–88.        Neuropediatrics, 21(1): 55–56.


            Volume 2 Issue 2 (2023)                         10                         https://doi.org/10.36922/td.1057
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