Page 42 - TD-3-4
P. 42

Tumor Discovery                                                     HIF1α treatments in renal cell carcinoma



            11.  Klatte T, Seligson DB, Riggs SB,  et  al. Hypoxia-inducible      doi: 10.1007/s12032-018-1217-1
               factor 1 alpha in clear cell renal cell carcinoma. Clin Cancer   22.  Drugs.com. Sutent (Sunitinib Malate) FDA Approval History.
               Res. 2007;13(24):7388-7393.
                                                                  Available from: https://www.drugs.com/history/sutent.html
               doi: 10.1158/1078-0432.CCR-07-0411                 [Last accessed on 2024 Jul 14].
            12.  Shen C, Beroukhim R, Schumacher SE, et al. Genetic and   23.  Motzer RJ, Hutson TE, Tomczak P, et al. Sunitinib versus
               functional studies implicate HIF1α as a 14q kidney cancer   interferon alfa in metastatic renal-cell carcinoma. N Engl J
               suppressor gene. Cancer Discov. 2011;1(3):222-235.  Med. 2007;356(2):115-124.
               doi: 10.1158/2159-8290.CD-11-0098                  doi: 10.1056/NEJMoa065044
            13.  Xu K, Ding Q, Fang Z, et al. Silencing of HIF-1α suppresses   24.  Summers J, Cohen MH, Keegan P, Pazdur R. FDA drug
               tumorigenicity of renal cell carcinoma through induction of   approval summary: Bevacizumab plus interferon for advanced
               apoptosis. Cancer Gene Ther. 2010;17(3):212-222.   renal cell carcinoma. Oncologist. 2010;15(1):104-111.
               doi: 10.1038/cgt.2009.66                           doi: 10.1634/theoncologist.2009-0250
            14.  Tassoudi A, Stefanidis I, Eleftheriadis T, Tzortzis V,   25.  Rini BI, Halabi S, Rosenberg JE,  et  al. Bevacizumab Plus
               Tassoudis V, Ioannou M. Study of hypoxia induced factor-  interferon alfa compared with interferon alfa monotherapy
               1alpha (HIF-1A) and carbonic anhydrase 9 (CAIX) in Clear   in patients with metastatic renal cell carcinoma: CALGB
               Cell Renal Cell Carcinoma (ccRCC).  Arch Nephrol Urol.   90206. J Clin Oncol. 2008;26(33):5422-5428.
               2021;4(2):50-62.
                                                                  doi: 10.1200/JCO.2008.16.9847
               doi: 10.26502/anu.2644-2833036
                                                               26.  Gupta S, Spiess PE. The prospects of pazopanib in advanced
            15.  Fallah J, Rini BI. HIF inhibitors: Status of current clinical   renal cell carcinoma. Ther Adv Urol. 2013;5(5):223-232.
               development. Curr Oncol Rep. 2019;21(1):6.
                                                                  doi: 10.1177/1756287213495099
               doi: 10.1007/s11912-019-0752-z
                                                               27.  Kim  JH,  Park  I,  Lee  JL.  Pazopanib  versus  sunitinib  for
            16.  Greenberger LM, Horak ID, Filpula D, et al. A RNA antagonist   the treatment of metastatic renal cell carcinoma patients
               of hypoxia-inducible factor-1α, EZN-2968, inhibits tumor   with poor-risk features.  Cancer  Chemother  Pharmacol.
               cell growth. Mol Cancer Ther. 2008;7(11):3598-3608.  2016;78(2):325-332.
               doi: 10.1158/1535-7163.MCT-08-0510                 doi: 10.1007/s00280-016-3093-8
            17.  Costa LJ, Drabkin  HA. Renal cell carcinoma: New   28.  Tyler T. Axitinib: Newly approved for renal cell carcinoma.
               developments in molecular biology and potential for   J Adv Pract Oncol. 2012;3(5):333-335.
               targeted therapies. Oncologist. 2007;12(12):1404-1415.
                                                                  doi: 10.6004/jadpro.2012.3.5.7
               doi: 10.1634/theoncologist.12-12-1404
                                                               29.  Motzer RJ, Penkov K, Haanen J, et al. Avelumab plus axitinib
            18.  Drugs.com.  Nexavar FDA Approval History. Available   versus sunitinib for advanced renal-cell carcinoma. N Engl J
               from:         https://www.drugs.com/history/nexavar.  Med. 2019;380(12):1103-1115.
               html#:~:text=fda%20approved%3a%20yes%20            doi: 10.1056/NEJMoa1816047
               %28first%20approved%20december%2020%2c%20
               2005%29,for%3a%20renal%20cell%20carcinoma%2c%20  30.  Center for Drug Evaluation and Research.  FDA Grants
               hepatocellular%20carcinoma%2c%20thyroid%20cancer   Regular Approval to Cabometyx for First-Line Treatment
               [Last accessed on 2024 Jul 14].                    of Advanced Renal Cell Carcinoma. U.S. Food and Drug
                                                                  Administration, FDA. Available from: https://www.
            19.  Escudier B, Eisen T, Stadler WM,  et al. Sorafenib in   fda.gov/drugs/resources-information-approved-drugs/
               advanced clear-cell renal-cell carcinoma.  N  Engl  J  Med.   fda-grants-regular-approval-cabometyx-first-line-
               2007;356(2):125-134.
                                                                  treatment-advanced-renal-cell-carcinoma#:~:text=on%20
               doi: 10.1056/NEJMoa060655                          december%2019%2c%202017%2c%20the,renal%20cell%20
                                                                  carcinoma%20(rcc) [Last accessed on 2024 Jul 14].
            20.  Kathuria-Prakash N, Drolen C, Hannigan CA, Drakaki  A.
               Immunotherapy and metastatic renal cell carcinoma:   31.  Choueiri TK, Halabi S, Sanford BL,  et al. Cabozantinib
               A  review of new treatment approaches.  Life  (Basel).   versus sunitinib as initial targeted therapy for patients with
               2021;12(1):24.                                     metastatic renal cell carcinoma of poor or intermediate
                                                                  risk: The alliance A031203 CABOSUN trial. J Clin Oncol.
               doi: 10.3390/life12010024
                                                                  2017;35(6):591-597.
            21.  Wiechno P, Kucharz J, Sadowska M,  et al. Contemporary
               treatment of metastatic renal cell carcinoma.  Med Oncol.      doi: 10.1200/JCO.2016.70.7398
               2018;35(12):156.                                32.  Center for Drug Evaluation and Research. FDA D.I.S.C.O.



            Volume 3 Issue 4 (2024)                         7                                 doi: 10.36922/td.4346
   37   38   39   40   41   42   43   44   45   46   47