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Tumor Discovery Desmoplastic small round cell tumor

3 h after admission. No autopsy was conducted according
to the wishes of the patient’s family.
3. Discussion

DSRCTs were first reported by Gerald and Rosai in 1989.
2
This condition occurs most frequently in young people,
and its peak incidence has been reported in people in
their 30s. It predominantly affects men and is exceedingly
rare in women. While it most frequently presents in the
peritoneum and omentum, occurrences at other sites,
including the pleura, ethmoid sinus, scalp, hands, posterior
cranial fossa, pancreas, ovaries, paratesticular region, and
kidneys, have been documented. 3-5
Clinical symptoms of primary gynecological disease
are abdominal distension with abdominal pain and ascites,
Figure 6. Multiple liver metastases after irradiation (contrast computed
6,7
tomography) mass palpation, constipation, anorexia, and weight loss.
More than 40% of patients have distant metastases at the
time of the initial diagnosis, mostly to the liver, lungs,
bones, and lymph nodes. Most cases develop as intra-
abdominal masses, which have an average size of 11 cm
by the time that they are diagnosed. Although diagnostic
3
imaging is useful, it often shows non-specific findings. The
8
patient had previously presented with asymptomatic lower
abdominal pain. The patient was diagnosed as having
asymptomatic hypercalcemia; post-surgery, their serum
calcium levels decreased to 9.3 – 9.9 mg/dL, and during
the period from recurrence to death, it stabilized at 9.1 –
9.7 mg/dL without an upward trend.
Examination findings are often recognized as large
tumors with internal heterogeneity on CT scans. Moreover,
MRI often shows high signal intensity on T2-weighted
images and equal signal intensity on T1-weighted images.
8
Figure 7. Increased liver metastasis after administration of lenvatinib and PET is often used to accurately detect early post-treatment
pembrolizumab (contrast computed tomography) recurrence. In this case, the imaging was characteristic.
9
The levels of the tumor marker CA125 are known to
increase. The tumor measured 10 cm, and pre-operative
10
CT revealed no distant metastasis. In addition, the tumor
markers CA125, CA19-9, and CEA values were elevated,
NSE remained below the cut-off, and LDH levels were
within normal ranges. However, post-recurrence, these
markers did not increase, implying that they were not
reliable indicators of disease status in later stages. This may
reflect a variation in tumor cell populations between the
initial treatment and recurrence.
According to the World Health Organization’s 2020
classification, the condition is classified as a peritoneal
tumor and is characterized by gene translocation, including
11
Figure 8. Computed tomography scan of the patient before death that of the EWSR-WT1 fusion gene. Macroscopically,
it appears as a solid mass, and the cut surface is white
no signs of pulmonary embolism. Her condition quickly and solid, which is sometimes accompanied by necrosis.
worsened, leading to cardiopulmonary arrest, and she died Histological features include epithelial-like tumor cells

Volume 4 Issue 2 (2025) 108 doi: 10.36922/td.7104