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Tumor Discovery DLBCL in the splenic hilar lymph node
and stage I/II DLCBL, 3,4,6,8,10,17 our case was managed References
postoperatively with three courses of the PvRCHP regimen 1. Coupland SE, Du MQ, Ferry JA, et al. The fifth edition of
due to concerns regarding potential poor prognosis. the WHO classification of mature B-cell neoplasms: Open
questions for research. J Pathol. 2024;262(3):255-270.
4. Conclusion
doi: 10.1002/path.6246
In this case, after surgical resection and subsequent gross
and microscopic examinations, it was determined that the 2. Shimizu-Kohno K, Kimura Y, Kiyasu J, et al. Malignant
lymphoma of the spleen in Japan: A clinicopathological
mass originated from the splenic hilar lymph node, despite analysis of 115 cases. Pathol Int. 2012;62:577-582.
pre-operative imaging studies (CT, PET/CT) suggesting
an intrasplenic tumor. Thus, even when imaging studies doi: 10.1111/j.1440-1827.2012.02844.x
indicate an intrasplenic mass, caution must be exercised 3. Shimono J, Miyoshi H, Kiyasu J, et al. Clinicopathological
regarding the possibility of lymphoma located outside the analysis of primary splenic diffuse large B-cell lymphoma.
spleen, potentially within the splenic hilar lymph node. Br J Haematol. 2017;178:719-727.
doi: 10.1111/bjh.14736
Acknowledgments
4. Rajendran T, Kini JR, Abna A, Prasad K. Clinical benefit
This study was conducted with the support of the medical of R-CHOP without splenectomy in stage I primary
staff at the Uji Tokushukai Medical Center. The authors splenic diffuse large B-cell lymphoma. BMJ Case
thank Professor Kouichi Ohshima, Professor Junji Rep. 2022;15(1):e246610.
Suzumiya, and Professor Motoko Yamaguchi for their doi: 10.1136/bcr-2021-246610
helpful comments on this case.
5. Wadsworth PA, Miranda RN, Bhakta P, et al. Primary
Funding splenic diffuse large B-cell lymphoma presenting as a splenic
abscess. EJHaem. 2023;4:226-231.
None. doi: 10.1002/jha2.642
Conflict of interest 6. Meng M, Riera CA, Mosquera J, Parikh HR, Singh A. Atypical
diffuse large B-cell lymphoma, primary splenic lymphoma
The authors declare no conflicts of interest. variant; A case report. Int J Surg Case Rep. 2023;111:108861.
Author contributions doi: 10.1016/j.ijscr.2023.108861
7. Yonghao Q, Yongyang W, Siqing Y, Lihua C, Shuju T.
Conceptualization: Naoyuki Anzai, Yutaka Shimazu, Comparison of survival outcomes of different treatment
Shinsaku Imashuku modalities for patients with primary splenic diffuse large B
Investigation: Ayaka Fukui, Naoki Nakajima, Shinsaku cell lymphoma. Ann Hematol. 2023;102(7):1857-1865.
Imashuku
Writing – original draft: Naoyuki Anzai, Yutaka Shimazu, doi: 10.1007/s00277-023-05171-z
Shinsaku Imashuku 8. Pirzada S, Hasnain A, Mankani AA, Zahid I. Primary splenic
Writing – review & editing: All authors diffuse large b-cell lymphoma: An atypical presentation.
Cureus. 2023;15(6):e40793.
Ethics approval and consent to participate doi: 10.7759/cureus.40793
The work was carried out following the Declaration of 9. Neves NM, Lopes AP, Coelho SC, Raimundo A, Mafra MM,
Helsinki as revised in 2013. This case report was approved Horta AB. Primary splenic diffuse large B-cell lymphoma:
by the institutional review board (Uji-Tokushukai Medical A case report. Eur J Case Rep Intern Med. 2023;10(7):003932.
Center Ethics Committee; IRB approval No. 2024-45). doi: 10.12890/2023_003932
The patient provided written consent to participate in this 10. Seijari MN, Kaspo S, Alshurafa A, Elfaieg A, Sarah A
study. Elkourashy SA. Primary splenic diffuse large B-cell
lymphoma: A case report and literature review of a rare
Consent for publication condition. Case Rep Oncol. 2024;17(1):447-453.
Written informed consent was obtained from the patient. doi: 10.1159/000537780
Availability of data 11. Justo I, Jiménez-Romero C, Suárez A, et al. Case study:
Splenic cyst deroofing complicated with B lymphoma. World
Data are available upon request from the authors. J Surg Oncol. 2024;22:231.
Volume 4 Issue 2 (2025) 103 doi: 10.36922/td.6742

