Page 23 - TD-4-2
P. 23

Tumor Discovery                                                         Melanoma exosomes in metastasis



               doi: 10.1016/j.ejps.2018.10.021                    scission. FEBS J. 2016;283:3288-3302.
            20.  Hoshino A, Kim HS, Bojmar L, et al. Extracellular vesicle      doi: 10.1111/febs.13688
               and particle biomarkers define multiple human cancers.
               Cell. 2020;182:1044-1061.e1018.                 32.  Henne WM, Buchkovich NJ, Emr SD. The ESCRT pathway.
                                                                  Dev Cell. 2011;21:77-91.
               doi: 10.1016/j.cell.2020.07.009
                                                                  doi: 10.1016/j.devcel.2011.05.015
            21.  Wortzel I, Dror S, Kenific CM, Lyden D. Exosome-mediated
               metastasis: Communication from a distance.  Dev Cell.   33.  Kalluri R, LeBleu VS. The biology, function, and biomedical
               2019;49:347-360.                                   applications of exosomes. Science. 2020;367:eaau6977.
                                                                  doi: 10.1126/science.aau6977
               doi: 10.1016/j.devcel.2019.04.011
                                                               34.  Ostrowski M, Carmo NB, Krumeich S, et al. Rab27a and
            22.  Rodrigues G, Hoshino A, Kenific CM, et al. Tumour
               exosomal CEMIP protein promotes cancer cell colonization   Rab27b control different steps of the exosome secretion
               in brain metastasis. Nat Cell Biol. 2019;21:1403-1412.  pathway. Nat Cell Biol. 2010;12:19-30; sup pp 11-13.
                                                                  doi: 10.1038/ncb2000
               doi: 10.1038/s41556-019-0404-4
                                                               35.  De Luca T, Pelosi A, Trisciuoglio D, et al. miR-211 and
            23.  Jella KK, Bukrinsky MI, Grizzi F. Exosomes, their
               biogenesis and role in inter-cellular communication, tumor   MITF modulation by Bcl-2 protein in melanoma cells. Mol
               microenvironment and cancer immunotherapy.  Vaccines.   Carcinog. 2016;55:2304-2312.
               2018;6:421.                                        doi: 10.1002/mc.22437
               doi: 10.3390/vaccines6040069                    36.  Radford KJ, Thorne RF, Hersey P. CD63 associates with
            24.  Wang G, Li J, Bojmar L, et al. Tumour extracellular vesicles   transmembrane 4 superfamily members, CD9 and CD81,
               and particles induce liver metabolic dysfunction.  Nature.   and with beta 1 integrins in human melanoma.  Biochem
               2023;618:374-382.                                  Biophys Res Commun. 1996;222:13-18.
               doi: 10.1038/s41586-023-06114-4                    doi: 10.1006/bbrc.1996.0690
            25.  Rodrigues G, Zhang H, Lyden D. Tumour vesicular   37.  Lee  YJ,  Shin  KJ,  Chae  YC.  Regulation  of  cargo  selection
               micromachinery uncovered. Nat Cell Biol. 2019;21:795-797.  in exosome biogenesis and its biomedical applications in
                                                                  cancer. Exp Mol Med. 2024;56:877-889.
               doi: 10.1038/s41556-019-0351-0
                                                                  doi: 10.1038/s12276-024-01209-y
            26.  Dai J, Su Y, Zhong S, et al. Exosomes: Key players in cancer
               and potential therapeutic strategy. Signal Transduct Target   38.  Hofmann UB, Houben R, Bröcker EB, Becker JC. Role
               Ther. 2020;5:145.                                  of matrix metalloproteinases in melanoma cell invasion.
                                                                  Biochimie. 2005;87:307-314.
               doi: 10.1038/s41392-020-00261-0
                                                                  doi: 10.1016/j.biochi.2005.01.013
            27.  Zhang H, Freitas D, Kim HS, et al. Identification of distinct
               nanoparticles and  subsets of extracellular  vesicles  by   39.  Tucci M, Mannavola F, Passarelli A, Stucci LS, Cives M,
               asymmetric  flow field-flow  fractionation.  Nat Cell  Biol.   Silvestris F. Exosomes in melanoma: A  role in tumor
               2018;20:332-343.                                   progression, metastasis and impaired immune system
                                                                  activity. Oncotarget. 2018;9:20826-20837.
               doi: 10.1038/s41556-018-0040-4
                                                                  doi: 10.18632/oncotarget.24846
            28.  Katzmann DJ. No ESCRT to the melanosome: MVB sorting
               without ubiquitin. Dev Cell. 2006;10:278-280.   40.  Lind EF, Ohashi PS. Mir-155, a central modulator of T-cell
                                                                  responses. Eur J Immunol. 2014;44:11-15.
               doi: 10.1016/j.devcel.2006.02.005
                                                                  doi: 10.1002/eji.201343962
            29.  Bojmar L, Kim HS, Tobias GC, et al. Extracellular vesicle
               and particle  isolation from  human  and murine cell  lines,   41.  Hussen BM, Hidayat HJ, Salihi A, Sabir DK, Taheri M,
               tissues, and bodily fluids. STAR Protoc. 2021;2:100225.  Ghafouri-Fard S. MicroRNA: A  signature for cancer
                                                                  progression. Biomed Pharmacother. 2021;138:111528.
               doi: 10.1016/j.xpro.2020.100225
                                                                  doi: 10.1016/j.biopha.2021.111528
            30.  Lee YJ, Shin KJ, Jang HJ,  et  al. GPR143 controls ESCRT-
               dependent exosome biogenesis and promotes cancer   42.  Li J, Li Q, Lin L, et al. Targeting the Notch1 oncogene by
               metastasis. Dev Cell. 2023;58:320-334.e328.        miR-139-5p inhibits glioma metastasis and epithelial-
                                                                  mesenchymal transition (EMT). BMC Neurol. 2018;18:133.
               doi: 10.1016/j.devcel.2023.01.006
                                                                  doi: 10.1186/s12883-018-1139-8
            31.  Alonso YAM, Migliano SM, Teis D. ESCRT-III and Vps4:
               A dynamic multipurpose tool for membrane budding and   43.  Zeng  B,  Chen  Y,  Chen  H, et al.  Exosomal miR-211-5p


            Volume 4 Issue 2 (2025)                         15                                doi: 10.36922/td.7108
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