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Tumor Discovery                                               Understanding glioblastoma invasion and therapy



            investigations into the ways human cancers are shaped by   Institute. Data Source(s): SEER Incidence Data, November
            the unique features of both central and peripheral nervous   2023 Submission (1975-2021), SEER 22 Registries; 2024.
            tissue. 190                                           Available from: https://seer.cancer.gov/statistics-network/
                                                                  explorer Last accessed on 2025 Apr 10].
            Acknowledgments                                    5.   Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy
            We wish to acknowledge an amazing scientist and mentor,   plus concomitant and adjuvant temozolomide for
            Dr. Arthur Alberts, who passed away from glioblastoma at   glioblastoma. N Engl J Med. 2005;352(10):987-996.
            the age of 52, as an inspiration for this review.     doi: 10.1056/NEJMoa043330

            Funding                                            6.   Bauman GS, Gaspar LE, Fisher BJ, Halperin EC,
                                                                  Macdonald DR, Cairncross JG. A  prospective study of
            Departmental funds from the Department of Cell and    short-course radiotherapy in poor prognosis glioblastoma
            Cancer Biology and the Department of Medical Education,   multiforme. Int J Radiat Oncol Biol Phys. 1994;29(4):835-839.
            College of Medicine and Life Sciences,  University of      doi: 10.1016/0360-3016(94)90573-8
            Toledo, supported this work.
                                                               7.   Whittle IR, Denholm SW, Gregor A. Management of patients
            Conflict of interest                                  aged over 60 years with supratentorial glioma: Lessons from
                                                                  an audit. Surg Neurol. 1991;36(2):106-111.
            The authors declare they have no competing interests.     doi: 10.1016/0090-3019(91)90227-z
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            Ethics approval and consent to participate            and core pathways. Nature. 2008;455(7216):1061-1068.
            Not applicable.                                       doi: 10.1038/nature07385
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            Not applicable.                                       2019;178(4):835-849.e21.
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            Availability of data
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            Volume 4 Issue 2 (2025)                         33                                doi: 10.36922/td.8578
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