Page 24 - manuscript_ijb05596

prospects of the combination of 3D printing and AI in the field of diabetic wound

healing.

Figure 5. Schematic process of 3D-printed hydrogels by DNA-induced biomineralization. Adapted
from ref. [62] .

3. The mechanism of 3D printed hydrogel in repairing diabetic wounds

Diabetic wounds were hindered in healing due to the pathological

microenvironment induced by persistent hyperglycemia, chronic inflammation and

cellular dysfunction, etc. The inherent design flexibility of 3D printing technology

23