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Figure 1. The cross-linking method and mechanism of 3D printing hydrogel.
2.Preparation method of 3D printed hydrogel
As a cutting-edge technology, 3D printing technology is deeply integrated with
hydrogels, which opens up a new path for the biomedical field, and effectively
overcomes the limitations of traditional cross-linking methods. At present, the
preparation methods of 3D printed hydrogels mainly include physical cross-linking,
chemical cross-linking, and biological cross-linking. In the following, we will introduce
these methods in detail.
2.1. Physical cross-linking method
Physical cross-linking method was one of the key methods to prepare a 3D printed
hydrogels. The core principle of the physical cross-linking method was to use non-
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