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Artificial Intelligence in Health                                       AI in AD – Diagnosis and monitoring



            driving, industrial automation, and the widespread use of   to diagnose and monitor effectively. Prompt and accurate
            cell phones. Recent developments have notably bolstered   identification is indispensable for the effective management
            the efficiency, accuracy, and productivity of AI-optimized   of AD. However, conventional diagnostic techniques
            workflows in the health-care industry. AI involves the   tend to heighten variability in diagnosis and may cause
            application of sophisticated computational algorithms   delays in the initiation of therapy, relying heavily on
            to simulate complex cognitive functions of humans,   clinical judgment. A promising avenue toward achieving
            accomplished through learning and adaptation to gathered   objective, accurate, and rapid diagnostic procedures lies in
            data. Over the past decades, there has been a marked increase   the integration of AI-based technology, which holds the
            in both research and application of AI in healthcare, with the   potential to revolutionize AD management. This review
            potential to completely transform the sector. 1-4  highlights the rationale behind the potential of AI in
              Similar to AI, the field of dermatology has experienced   completely  transforming  AD  monitoring  and  diagnostic
            rapid growth owing to advancements in technology and   procedures. While acknowledging the efficiency of AI,
            inventions. This evolution has brought dramatic changes   it also emphasizes the importance of problem-solving
            in the diagnosis and treatment of dermatological illnesses.   and fostering teamwork. These initiatives are essential in
                                                               maximizing the benefit of AI in improving the precision
            Computer algorithms have proven to be invaluable tools for   and effectiveness of AD monitoring and diagnosis
            dermatologists, particularly in diagnosing diseases such as   procedures.
            malignant melanoma.  Dermatology boasts a vast archive
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            of clinical, dermatoscopic, and dermatopathological   2. Methodology
            images, positioning it as a leader in the application of AI
            in medicine. Therefore, having a basic understanding of   In conducting a systematic literature review on the
            AI becomes essential for designing and evaluating medical   contemporary utilization of AI in diagnosing and
            research in this area. Consequently, investigating the   monitoring individuals with AD, we implemented a
            potential uses of AI in dermatological practice becomes   rigorous methodology for gathering pertinent articles
            imperative.                                        from prominent databases, including PubMed, Springer,
                                                               and Elsevier. The search utilized specific keywords, such
              Atopic dermatitis (AD) is a common inflammatory   as  “Artificial  intelligence,”  “Machine  learning,”  “Deep
            skin disease that affects a significant proportion of   learning,” and “Atopic dermatitis.” Article selection
            dermatology patients worldwide, estimated to affect 1 –   prioritized  peer-reviewed  studies  in  dermatology  that
                                   6
            2% of the global population.  Notably, between the 1980s   specifically examined the integration of AI in the diagnosis
            and the early 2000s, there was a discernible global surge   and monitoring of AD. Articles that failed to meet these
            in the prevalence of AD, particularly pronounced among   criteria or published in languages other than English
            children under the age of five, with rates ranging from 10%   were  systematically excluded from the  study. Following
            to 16.5%.  Individuals with AD exhibit a wide range of   data extraction, we summarized the key findings, and
                   7,8
            clinical symptoms, categorized into six distinct subtypes   the synthesized information was then carefully compiled
            based on their origin. Among these, the most prevalent   into a comprehensive literature review, providing valuable
            subtype is early-onset, early-resolving; nonetheless,   insights into the current state of knowledge, addressing
            recurrence is frequently observed, with less severe   challenges, and advocating for collaboration across intra-,
            symptoms than the original episode.  The three main   inter-, trans-, and multi-disciplinary domains to optimize
                                          9,10
            symptoms of AD – skin inflammation, compromised skin   the benefits of AI in improving the accuracy of AD
            barrier function, and persistent itching-exerta negative   diagnosis.
            influence on the lives of those afflicted, significantly
            impacting their quality of life and level of satisfaction with   3. Principle of AI
            therapy. 11-13   Moreover,  patients’  adherence  to  treatment   AI encompasses various computational subfields, including
            procedures is severely hindered by these symptoms. 14-16    machine learning (ML) and natural language processing
            Staphylococcus aureus colonization often arises as a result of   (NLP), enabling computer systems to mimic human
            skin barrier dysfunction, exacerbating the degradation of   cognitive functions (Figure  1). At present, ML, where
            the barrier function. 17,18  Notably, AD is linked to systemic   computers anticipate data without explicit programming,
            inflammatory conditions, such as metabolic syndrome   stands as the frontier of AI advancement. Essentially,
            and cardiovascular disease, despite not being as visually   computers “learn” from data, offering analyses without
            conspicuous as psoriasis. 19                       explicit  guidance  on  trait  prioritization.  Dermatologists
              Given its broad spectrum of clinical symptoms, AD   offer compelling examples, such as identifying melanomas
            presents as an unexpected illness that can prove challenging   from clinical images,  predicting the effectiveness of
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            Volume 1 Issue 2 (2024)                         49                               doi: 10.36922/aih.2775
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