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Artificial Intelligence in Health                                          Machine learning in arthroplasty



            efficiency in surgical planning.  The attempted model   to several established clinical measurement tools: ASES
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            displayed a position error of 2.4 mm and an angular error   scores, Constant, University of California Los Angeles,
            of 6.51° compared to manually computed measurements,   Simple Shoulder Test, and Shoulder Pain and Disability
            indicating the feasibility of applying such ML models to   Index. Ultimately, the six-question score provided an
            TSA.  Table 3 displays the summaries of relevant studies   equivalent or better validity, responsiveness, and clinical
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            exploring the use of AI in implant positioning related to   interpretability value compared to previously developed
            TSA.                                               tools,  paving  the  way for  ML  applications  in  creating
                                                               PROM assessments. Table 3 presents the summary of key
            4.2. Outcome prediction                            studies assessing the role of AI in predicting PROMs in
            4.2.1. PROMs                                       patients undergoing TSA.
            Shoulder procedures are no different from other areas of   4.2.2. Readmissions, LOS, cost
            orthopedics, given that patient perspectives on outcomes   Hospital stay length and patient-accrued costs can directly
            and quality of care have become increasingly important
            in orthopedics. Therefore, it is expected that AI has   affect patient satisfaction and the perceived value of
            moved beyond lower extremity procedures, in an attempt   shoulder operations. The ability to anticipate deviations
            to anticipate the factors that go into more challenging   from normal care can allow patients to anticipate
                                                               prolonged hospital stays and increased costs. Biron
            shoulder operations. Specific to shoulder procedures,   et al.  employed a TSA-specific ML model to predict
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            Polce et al.  developed an ML algorithm to predict patient   patients who would experience a hospital stay for less
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            satisfaction 2 years post-operation following TSA, further   than a day. Their model produced an AOC of 0.77 with
            evaluating predictive factors that could affect patient   moderate reliability.  In  addition, Karnuta  et  al.  used
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            satisfaction.   Their  most successful  algorithm displayed   artificial neural networks (ANN) to predict LOS, discharge
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            an AUROC value of 0.80 and a Brier score of 0.14. A Brier   disposition, and inpatient costs in patients undergoing
            score measures the accuracy of a prediction, where zero   shoulder arthroplasty secondary to chronic degenerative
            is the best possible score. The five most important inputs   changes and traumatic injury. In patients with a chronic
            to the algorithm were baseline Single Assessment Numeric   degenerative disease, respective accuracies for predicting
            Evaluation score, exercise and activity, insurance status,   LOS, discharge disposition, and cost were 91.8%, 73.1%,
            diagnosis, and pre-operative duration of symptoms.  A   and 76.5.  In patients with traumatic presentations, the
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            more recent use of ML is to use natural language processing   accuracy was  slightly  diminished  for  predicting  LOS,
            models to automatize and streamline PROMs. Menendez   discharge disposition, and cost, which were 79.1%, 72%,
            et al.  aimed to enhance  the efficiency  of categorizing   and 70.3%, respectively. 75
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            negative patient comments following TSA. Their model
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            demonstrated a 98.5% accuracy, reliably classifying   Readmissions were examined by Arvind  et al.
            patient comments. These ML applications mark a wave   through ML employment to predict 30-day readmission
            of autonomization in research, making it possible for   following primary TSA. The maximum derived C-statistic
            orthopedic surgeons to conduct research despite a possible   (equivalent to AUROC) was 0.74, and the peak f1-score
            lack of personnel.                                 (combines precision and sensitivity to quantify accuracy)
                                                               was 0.18  . Gowd  et al.  achieved a prediction for
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              Moreover, ML algorithms have been employed to    unplanned  readmission following TSA  with  an  AUROC
            predict American Shoulder and Elbow Surgeon (ASES)   of 0.66, indicating slightly less reliability. However,
            scores based on pre-operative data, including demographic   they also added a model that predicted inpatient costs,
            information, computed tomography imaging, pre-     demonstrating a higher AUROC of 0.87.  Table 3 outlines
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            operative VAS pain score, and pre-operative ASES scores.   the relevant studies investigating the use of AI in predicting
            The model predicted patient-reported improvement with   readmission, LOS, and cost to patients related to TSA.
            sensitivities between 0.84 and 0.95. 72
              Beyond predictive measures, ML has been used to   4.2.3. Complications
            develop a novel shoulder  outcomes measure called the   Complications related to TSA can have multitudes of effects
            Shoulder Arthroplasty Smart (SAS) score. Using data from   on patient mortality, functional outcomes, and satisfaction.
            3,667  patients receiving anatomic or reverse shoulder   ML algorithms  have  displayed  capabilities in  potentially
            arthroplasty with a minimum 2-year follow-up, the ML   planning for these unanticipated complications. Gowd
            algorithm chose six outcome measures, assessed by three   et al.  developed ML algorithms to anticipate any operative
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            objective questions regarding motion input and three   adverse events, anemia necessitating blood transfusion,
            subjective patient measures.  The SAS was then compared   and extended hospital stay. Accuracies for predicting all
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            Volume 2 Issue 2 (2025)                         22                               doi: 10.36922/aih.3278
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