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Artificial Intelligence in Health                              Opportunities for AI-based arrhythmia screening



            and  temporal  pathological  conditions.  This  provides   include but are not limited to, heart attack, arrhythmias, heart
            additional  information  beyond  standard  cardiac  rhythm   failure, cardiomyopathy, and heart valve disease. Additional
            identifiers, such as heart rate and various specific interval   diagnoses of other pathological conditions, including several
            measurements.                                      rare or atypical cardiac depolarization patterns, are not
              To isolate the true depolarization sequence, noise must   listed due to their infrequent occurrence and the current
            be eliminated using techniques such as cutoff filtering,   limitations of the ongoing research and development
            frequency filtering, wavelet filtering, and Wiener filtering.   program. Furthermore, many arrhythmias have yet to be
            These methods can be applied to eliminate motion artifacts,   investigated for AI-based discovery. For quantifiable time-
            impedance mismatches, and tissue conductivity variation.  specific conditions, refer to Figure 1.
              The data acquisition device will also incorporate   5. Conclusion
            electronic  mechanisms  for  signal  (pre-)  processing,   Artificial intelligence-supported diagnostics offer a
            including gain adjustment, offset correction, frequency   powerful tool for rapid patient screening and identification
            filtering (primarily low-pass), and  hardware-based   of cardiac abnormalities. However, a thorough investigation
            automated noise reduction. 65,66  In addition, frequent and
            sequential repetition of deviations in the ECG pattern   into the root cause of these deviations is essential to
                                                                                                           65,66
            can be analyzed using Fourier analysis, wavelet filtering,   develop a comprehensive, patient-specific treatment.
            and  matched  filter  analysis.  The  wavelet,  matched  filter,   The growing recognition of AI’s accuracy and reliability
            and Wiener filtering analysis rely on an accurate base   in diagnostics is gaining widespread acceptance. In
            template for analysis, which must be customized to match   particular, AI-driven screening and risk-stratification,
                                                               based on comparison with specific signal patterns of
            the individual’s specific history. The choice of template   a  broad  range  of  pathological  cardiac  conditions,  has
            used  for  screening  and diagnosis  is typically  based  on
            the boundary conditions of the patient group being   demonstrated significant value. These tools not only
            investigated, such as athlete status, activity level, age,   improve diagnostic precision but also save time in clinical
            gender, genetics, weight, habits, and disabilities. Women   settings. Time-domain and frequency-domain filtering
            are often misdiagnosed due to the use of male-centered   and analyses have long been used with excellent results.
            cardiac rhythm templates. Therefore, great care must   However, the introduction of more advanced techniques,
            be taken to apply the appropriate screening boundary   such as wavelet analysis and matched filtering, has enabled
            conditions and construct a respective diagnostic template   the identification of complex disease patterns with higher
            based on available prior monitoring data for the individual   accuracy. AI-based diagnosis can statistically determine
            or a similar group. By utilizing existing data streams under   the prevalence of certain arrhythmogenic conditions by
            healthy conditions, neural network-generated templates   matching ECG data with predefined templates or groups
            can be used to detect deviations and reconstruct a template   of arrhythmias. Each classification may encompass various
            that matches the suspected pathological condition through   cardiac rhythm morphologies. In addition, AI can offer
            machine learning analysis.                         details about the duration of pathological events and the
                                                               frequency of specific phenomena over time, which may
              The use of AI and deep learning techniques can   indicate the presence of one or more arrhythmias. The
            be enhanced through convolutional neural network   feasibility  study  described  here  provides  preliminary
            processing to provide scheduled updates, as well as to   insights  into  the  use  of  AI  for  cardiac  health  screening.
            verify  and validate  the sampling  templates  used  in each   Nonetheless, further analysis by a physician, incorporating
            analytical procedure for the individual patient and their   the patient’s history and likely additional tests, will lead to a
            corresponding patient group selected as the baseline. 46-59    patient-specific diagnosis. Alternatively, the physician may
            The automated ECG analysis routines currently extract   treat the arrhythmia spectrum identified by AI as a broad-
            the following values from the data: corrected QT interval,   based issue, addressing it with a single, multipurpose
            heart rate, P height, PQR-interval, QRS width, QT interval,   medication. 67,68  Several drugs currently available on the
            R height, RR interval, and ST interval. 61         market can effectively manage a wide range of cardiac
              Several verified diagnoses, as well as several desired   rhythm problems. However, certain conditions, such as
            requirements for cardiac health monitoring, are listed in   VF, cannot be controlled pharmacologically and require
            Table 2. Some of these diagnostic modalities are applicable to   an implantable cardioverter defibrillator. Similarly,
            3-lead, 5-lead, and 12-lead ECG. 64-66  In addition, numerous   other arrhythmias that cannot be well-controlled by
            diagnostic techniques are currently being developed and are   pharmaceutical means require the use of a pacemaker,
            in various stages of preparation for commercial release under   as determined based on follow-up examination by the
            regulatory constraints. The associated pathological conditions   physician. 67-74


            Volume 2 Issue 3 (2025)                        120                               doi: 10.36922/aih.8468
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