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                rather than relying on a centralized cloud infrastructure.   environmental modeling and simulations. It discusses
                The  research  investigates  the  integration  of  artificial   the systematic process required for successful
                intelligence  with edge computing,  emphasizing  its   application management, involving expertise in various
                prospects for immediate data analysis and decentralized   scientific domains.  The study systematically reviews
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                decision-making in health care, smart cities, industrial   tools for maximizing biological information of genes,
                automation, and autonomous systems. It emphasizes the   summarizing over 300 tools, databases, and algorithms
                importance of compact artificial intelligence models and   for analyzing differentially expressed genes. It provides
                strong security mechanisms.  ORCAN is an internet-  guidelines  to  assist  researchers  in  effectively  mining
                                         48
                based meta-server for single-click  protein sequence   gene functions and interactions. The review highlights
                labeling that increases sensitivity and accuracy by 1 –   trajectory inference tools such as Monocle, Slingshot,
                2% while correcting conflicting orthology predictions.    and  scVelo,  focusing  on their  unique  features  and
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                The study explores the application of knowledge graph   applications.  It  discusses gene-phenotype  association
                embedding  (KGE) models  in biological  systems,    analysis  methodologies,  including  FUSION and
                highlighting their ability to represent complex biological   PrediXcan, to uncover genetic  variations  linked  to
                knowledge as graphs. KGE models demonstrate superior   diseases. 55
                predictive  accuracy  and  scalability  in  tasks such as   Another evaluation  investigates  sludge extract
                predicting  drug-target  interactions  and polypharmacy   management, with an emphasis on resource recuperation
                side effects. The study discusses the challenges of data   and  reduction  of environmental  impacts  for zero-
                quality and interpretability associated with KGE models   waste discharge. It addresses the  issues, constraints,
                while emphasizing their potential in various biological   and solutions for maximizing reuse for ecological and
                applications,  including genomics and proteomics.   regulatory  adherence.  Badawi  et  al. investigate  the
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                Overall, KGE models are positioned as a promising tool
                for advancing  biological  data  analysis  and predictive   application  of  orange  peel-derived  activated  carbon
                modeling. 50                                        supported by cobalt ferrite as a ferromagnetic scrubber
                  An additional  study criticizes  the  present  default   for the treatment of effluent from pulp and paper mills.
                assumptions regarding  product consumption  in      Its promise as an environmentally friendly approach is
                Registration, Evaluation, Authorisation, and Restriction   indicated by the findings, which demonstrate excellent
                of Chemicals  standards for chemical  emissions,    rates of pollution removal. 57
                claiming that these values are excessively cautious and
                geographically  constrained.   The project  investigates   3. Methodology
                                         51
                the potential  of metabolomics  in drug development,
                focusing on its applications  in clinical  pathology,   3.1. Dataset preprocessing
                biomarker  identification,  and  metabolic  subtyping.   There are  188  molecular  graphs  in  the  MUTAG
                It  focuses on the  application  of machine  learning   dataset.  Atoms are shown as nodes, and chemical
                methods to analyze complicated metabolic data.  The   linkages as edges in a graph that represents each
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                study proposes a machine  learning-powered Perturb   molecule. Carcinogenic (1) and non-carcinogenic
                and Observe (P&O) algorithm, named artificial neural   (0) labels are applied to each graph. Normalizing the
                network+P&O, enhancing  conventional  methods  for   node characteristics (atom types) to a range of 0 – 1
                maximum  power  point  tracking.  The  artificial  neural   is  the  first  step  in  preprocessing  the  dataset.  After
                network model predicts the duty ratio, improving    that, the dataset is divided into testing (20%) and
                convergence  speed  and  energy yield  compared  to   training (80%) sets. G = (V, E) is the representation
                traditional  P&O algorithms.  The proposed algorithm   of each molecular network in the dataset, where  V
                effectively  reduces  the  number  of  iterations  needed   stands for the set of nodes (atoms) and E for the set
                to reach the maximum power point, ensuring optimal   of  edges  (bonds).  Each  node  represents  atom  types
                performance. 53                                     as one-hot vectors, and characteristics such as bond
                  An additional study focuses on managing compute-  types (single, double, etc.) are linked to edges.  To
                intensive  applications  for high-performance  systems   guarantee uniform feature ranges, node features were
                to  enhance  operational  effectiveness.  It  highlights   normalized using min-max scaling.  An adjacency
                the challenges in designing and deploying high-     matrix A was constructed for each network to encode
                fidelity  applications  for  domain  experts.  The  study   connections. If nodes I and J are linked, then Aij = 1,
                emphasizes the importance of computational power in   and if not, Aij = 0.



                Volume 22 Issue 3 (2025)                        94                           doi: 10.36922/AJWEP025070041
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