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Advanced Neurology                                                  Targets and medications for AVM of CNS



            48.  Meng J, Okeda R, 2001, Histopathological structure of the   KRAS/BRAF somatic mutations in brain and spinal cord
               pial arteriovenous malformation in adults: Observation by   arteriovenous malformations. Brain, 142(1): 23-34.
               reconstruction of serial sections of four surgical specimens.      https://doi.org/10.1093/brain/awy307
               Acta Neuropathol, 102(1):63-68.
                                                               59.  Fish JE, Suarez CP, Boudreau E, et al., 2020, Somatic gain
               https://doi.org/10.1007/s004010000351
                                                                  of  kras  function  in  the  endothelium  is  sufficient  to  cause
            49.  Chen W, Guo Y, Walker EJ,  et al., 2013, Reduced mural   vascular malformations that require MEK but not PI3K
               cell coverage and impaired vessel integrity after angiogenic   signaling. Circ Res, 127(6): 727-743.
               stimulation in the Alk1-deficient brain. Arterioscler Thromb      https://doi.org/10.1161/CIRCRESAHA.119.316500
               Vasc Biol, 33(2): 305-310.
                                                               60.  Park ES, Kim S, Huang S, et al., 2021, Selective endothelial
               https://doi.org/10.1161/ATVBAHA.112.300485
                                                                  hyperactivation of oncogenic KRAS induces brain
            50.  Baeyens N, Larrivée B, Ola R, et al., 2016, Defective fluid   arteriovenous malformations in mice.  Ann Neurol, 89(5):
               shear stress mechanotransduction mediates hereditary   926-941.
               hemorrhagic telangiectasia. J Cell Biol, 214(7): 807-816.
                                                                  https://doi.org/10.1002/ana.26059
               https://doi.org/10.1083/jcb.201603106
                                                               61.  Edwards EA, Phelps AS, Cooke D, et al., 2020, Monitoring
            51.  Winkler EA, Birk H, Burkhardt JK, et al., 2018, Reductions   arteriovenous malformation response to genotype-targeted
               in  brain pericytes  are associated  with  arteriovenous   therapy. Pediatrics, 146(3):e20193206.
               malformation  vascular  instability.  J   Neurosurg,      https://doi.org/10.1542/peds.2019-3206
               129(6): 1464-1474.
                                                               62.  Nicholson CL, Flanagan S, Murati M, et al., 2022, Successful
               https://doi.org/10.3171/2017.6.JNS17860
                                                                  management of an arteriovenous malformation with
            52.  Lebrin F, Srun S, Raymond K,  et al., 2010, Thalidomide   trametinib in a patient with capillary-malformation
               stimulates vessel maturation and reduces epistaxis in   arteriovenous malformation syndrome and cardiac
               individuals with hereditary hemorrhagic telangiectasia. Nat   compromise. Pediatr Dermatol, 39(2): 316-319.
               Med, 16(4): 420-428.
                                                                  https://doi.org/10.1111/pde.14912
               https://doi.org/10.1038/nm.2131
                                                               63.  Lekwuttikarn R, Lim YH, Admani S, et al., 2019, Genotype-
            53.  Invernizzi R, Quaglia F, Klersy C, et al., 2015, Efficacy and   guided medical treatment of an arteriovenous malformation
               safety of thalidomide for the treatment of severe recurrent   in a child. JAMA Dermatol, 155(2): 256-257.
               epistaxis in hereditary haemorrhagic telangiectasia: Results      https://doi.org/10.1001/jamadermatol.2018.4653
               of a non-randomised, single-centre, phase 2 study. Lancet
               Haematol, 2(11):e465-e473.                      64.  Al‐Samkari H, Eng W, 2022, A precision medicine approach
                                                                  to hereditary hemorrhagic telangiectasia and complex
               https://doi.org/10.1016/S2352-3026(15)00195-7
                                                                  vascular anomalies. J Thromb Haemost, 20(5): 1077-1088.
            54.  Ge Z, Chen H, Gao Y, et al., 2011, Efficacy of thalidomide      https://doi.org/10.1111/jth.15715
               for refractory gastrointestinal bleeding from vascular
               malformation. Gastroenterology, 141(5): 1629-1637.e1-4.   65.  Winkler E, Wu D, Gil E, et al., 2022, Endoluminal biopsy for
                                                                  molecular profiling of human brain vascular malformations.
               https://doi.org/10.1053/j.gastro.2011.07.018
                                                                  Neurology, 98(16):e1637-e1647.
            55.  Tseng S, Pak G, Washenik K,  et  al., 1996, Rediscovering      https://doi.org/10.1212/WNL.0000000000200109
               thalidomide: A review of its mechanism of action, side effects,
               and potential uses. J Am Acad Dermatol, 35(6):969-979.   66.  Nguyen HL, Boon LM, Vikkula M, 2022, Trametinib as a
                                                                  promising therapeutic option in alleviating vascular defects
               https://doi.org/10.1016/S0190-9622(96)90122-X
                                                                  in an endothelial KRAS-induced mouse model. Hum Mol
            56.  Couto JA, Huang AY, Konczyk DJ,  et al., 2017, Somatic   Genet, ddac169.
               MAP2K1 mutations are associated with extracranial      https://doi.org/10.1093/hmg/ddac169
               arteriovenous  malformation.  Am  J  Hum  Genet,
               100(3):546-554.                                 67.  Liu AS, Mulliken JB, Zurakowski D, et al., 2010, Extracranial
                                                                  arteriovenous  malformations:  Natural  progression
               https://doi.org/10.1016/j.ajhg.2017.01.018
                                                                  and recurrence after treatment.  Plast Reconstr Surg,
            57.  Morita  H,  Komuro  I,  2018,  Somatic  activating  KRAS   125(4): 1185-1194.
               mutations in arteriovenous malformations of the brain.      https://doi.org/10.1097/PRS.0b013e3181d18070
               N Engl J Med, 378(16): 1561-1562.
                                                               68.  Murphy PA, Kim TN, Lu G,  et al., 2012, Notch4
               https://doi.org/10.1056/NEJMc1802190
                                                                  normalization reduces  blood vessel  size  in arteriovenous
            58.  Hong T, Yan Y, Li J,  et al., 2019, High prevalence of   malformations. Sci Transl Med, 4(117): 117ra8.


            Volume 1 Issue 3 (2022)                         10                      https://doi.org/10.36922/an.v1i3.211
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