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Advanced Neurology BRRS: A screening and monitoring tool for better prognosis in AD
Table 1. (Continued).
Name: Sex: Age: Education: Date:
Original score (O) Patient’s score
O 0 O 1 O 2
Parietal region Group score:
Functional damage (add 100 points).
Structural damage: White matter (add 100 points).
Structural damage: Gray matter (add 100 points).
Compensation appears in function (add 100 points).
Compensation appears in structure (add 100 points).
Decompensation or the previously observed compensation disappears: Each disappearance (add 100 points).
WMH (add 100 points).
Temporal region Group score:
Functional damage (add 100 points).
Structural damage: White matter (add 100 points).
Structural damage: Gray matter (add 100 points).
Compensation appears in function (add 100 points).
Compensation appears in structure (add 100 points).
Decompensation or the previously observed compensation disappears: Each disappearance (add 100 points).
WMH (add 100 points).
Occipital region Group score:
Functional damage (add 100 points).
Structural damage: White matter (add 100 points).
Structural damage: Gray matter (add 100 points).
Compensation appears in function (add 100 points).
Compensation appears in structure (add 100 points).
Decompensation or the previously observed compensation disappears: Each disappearance (add 100 points).
WMH (add 100 points).
Cerebellar region Group score:
Functional damage (add 100 points).
Structural damage: White matter (add 100 points).
Structural damage: Gray matter (add 100 points).
Compensation appears in function (add 100 points).
Compensation appears in structure (add 100 points).
Decompensation or the previously observed compensation disappears: Each disappearance (add 100 points).
WMH (add 100 points).
Total score S S S
0 1 2
Note
Aβ, beta-amyloid; BMI, body mass index; CSF, cerebrospinal fluid; WMH, white matter hyperintensity.
prevention [14,15] . It is divided into three groups: Basic The last group relates to comorbidities, such as diabetes,
information, lifestyle, and comorbidities. The basic head trauma, cerebrovascular disease, cardiovascular
information group consists of five items, namely, age , disease, depression, and hyperhomocysteinemia . Except
[14]
[14]
sex [16-18] , education [14,18,19] , AD pathological biomarkers for the weight item and items that have not been tested
detected in blood or cerebrospinal fluid [20-22] , and AD risk or scored points previously, there are often not too many
genes [23-25] . The lifestyle group comprises six items that are changes in the assessment of the original score. With regard
associated with weight, diet, living environment, and sleep. to the items that have originally scored points, despite the
Volume 1 Issue 3 (2022) 5 https://doi.org/10.36922/an.v1i3.208

