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Advanced Neurology A novel marker for healthy intracranial arteries

A B

C D

E F

G H

I J

Figure 1. The examples of Fried-Breadstick signs. (A) The Fried-Breadstick sign (arrows) is shown on MIP images. (B) The real-life Fried-Breadstick.
(C-E) Normal fried-breadstick signs: A continuous longitudinal line of signal loss at the center of the ICA lumen from C6 to C7 segments, which can
extend to MCA. (F-I) Abnormal fried-breadstick signs: The signal loss extends to ACA (F) and only exists in the C6 segment (G) or C7 segment (H-I).
(J) The absence of Fried-Breadstick sign: no signal loss at all. The black lines in the artery illustrations and the thin arrows on MIP images (C-I) indicate
the signal loss in ICA. The thick arrows (F-J) indicate the MCA stenosis.
Abbreviations: ACA: Anterior cerebral artery; ICA: Internal carotid artery; MCA: Middle cerebral artery; MIP: Maximum intensity projection;
PCoA: Posterior communicating artery.
intraobserver agreement, one of the readers repeated the observer and intra-observer agreement of the FB sign was
[15]
image analysis 1 month after the first analysis. The inter- assessed using kappa (κ) statistics .

Volume 2 Issue 4 (2023) 3 https://doi.org/10.36922/an.1238