Page 110 - AN-4-3

Advanced Neurology ADRD comorbidities and senescence

Table 3. Risk ratios of prevalence rates in ICD‑10 chapters
Demographic characteristics Risk ratios
Color ICD‑10 codes ICD‑10 diagnosis categories ADRD aged 65 – 80 ADRD aged ADRD aged No ADRD aged
coding versus No ADRD 90+ versus No 90+ versus 90+ versus No
aged 65 – 80 (A) ADRD aged 90+ (B) ADRD aged ADRD aged
65 – 80 (C) 65 – 80 (D)
A00-B99 Certain infectious and parasitic 2.0 2.1 1.0 1.0
diseases
C00-D49 Neoplasms 1.2 1.2 0.9 0.9
D50-D89 Diseases of the blood and 2.3 1.9 1.1 1.3
blood-forming organs and
certain disorders involving the
immune mechanism
E00-E89 Endocrine, nutritional, and 1.5 1.6 1.0 1.0
metabolic diseases
F01-F99 Mental, behavioral, and 3.4 4.7 1.0 0.7
neurodevelopmental disorders
G00-G99 Diseases of the nervous system 2.3 2.3 0.9 0.9
H00-H59 Diseases of the eye and adnexa 1.5 1.5 1.1 1.2
H60-H95 Diseases of the ear and mastoid 1.7 1.8 1.4 1.3
process
I00-I99 Diseases of the circulatory 1.5 1.5 1.1 1.1
system
J00-J99 Diseases of the respiratory 1.6 1.7 1.1 1.0
system
K00-K95 Diseases of the digestive 1.6 1.7 1.0 1.0
system
L00-L99 Diseases of the skin and 1.6 1.7 1.0 1.0
subcutaneous tissue
M00-M99 Diseases of the musculoskeletal 1.4 1.5 1.1 0.9
system and connective tissue
N00-N99 Diseases of the genitourinary 1.7 1.7 1.1 1.1
system
O00-O9A Pregnancy, childbirth, and the n/a n/a 1.0 n/a
puerperium
P00-P96 Certain conditions originating n/a n/a n/a n/a
in the perinatal period
Q00-Q99 Congenital malformations, 1.7 1.6 0.8 0.8
deformations, and
chromosomal abnormalities
R00-R99 Symptoms, signs, and 1.4 1.3 1.0 1.1
abnormal clinical and
laboratory findings, not
elsewhere classified
S00-T88 Injury, poisoning, and certain 1.8 1.8 1.1 1.1
other consequences of external
causes
U00-U85 Codes for special purposes 2.5 2.3 0.9 1.0
V00-Y99 External causes of morbidity 2.4 2.1 1.2 1.4
Z00-Z99 Factors influencing health status 1.2 1.3 1.0 0.9
and contact with health services
Note: Risk ratios were calculated for cohort comparisons based on the prevalence of ICD-10 codes between two cohort groups.
Abbreviation: ADRD: Alzheimer’s disease and related dementias; ICD-10: International classification of diseases, tenth revision.

Volume 4 Issue 3 (2025) 104 doi: 10.36922/an.4046