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Advances in Radiotherapy
            & Nuclear Medicine                                               SUVmax relating to patient and tumor factors




            Table 5. The relationship between various factors with the SUVmax as indicated by Spearman’s correlation and Chi‑square test
            Factors                                              SUVmax
                           Correlation value    Pc        Linear association by Chi‑square  Pc     Comment
            Age group          0.051           0.583               0.258                0.611      Non-significant
            Gender             0.094           0.314               0.802                0.370      Non-significant
            System             −0.086          0.356               0.871                0.351      Non-significant
            Histology          0.237           0.01                5.107                0.024      Significant
            Grade              −0.064          0.494               0.028                0.867      Non-significant
            Stage              0.048           0.608               0.297                0.586      Non-significant
            Note: c is based on normal approximation. P<0.05 is statistically significant. Abbreviation: SUVmax: Maximum standardized uptake value.

            Table 6. Variables selection and regression analysis factors
            Role/function in generalized regression model
            Variables selection for regression equation
             System                                           Predictor
             Age                                              Predictor
             Grade                                            Predictor
             System                                           Merge categories to maximize association with target
             Age                                              Trim outliers
             Grade                                            Merge categories to maximize association with target
                                                   Results of regression analysis
            Variables                                         B (coefficient)  Standard error  T          P
            (Constant)                                           12.728          2.342        5.435      0.000
            Age (years)                                          0.033           0.033        1.017      0.311
            Grade                                                0.158           0.474        0.333      0.739
            System                                               -0.515          0.441        -1.167     0.246
            Note: P<0.05 is statistically significant.


                        A                                  B



















            Figure 2. Regression plotted as (A) normal probability-probability plot showing fulfillment of criteria of normal distribution and (B) scatterplot showing
            the concentration of predicted values on a single area.
            Abbreviations: Cum Pro: Cumulative probability; SUV : Maximum standardized uptake value.
                                              max
            histologies and tumor sites. These limitations hinder the   sample size would have increased statistical power and
            interpretation and generalization of our results. A larger   facilitated the application of the boosting method for the


            Volume 1 Issue 2 (2024)                         6                       https://doi.org/10.36922/arnm.2032
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