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Advances in Radiotherapy
            & Nuclear Medicine                                                       3D-PT-assisted CT-guided  I RSI
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            Figure 3. The flowchart of three-dimensional-printed template-assisted computed tomography-guided iodine-125 radioactive seed implantation for head
            and neck cancer.
            Abbreviations: 3D-PCT: 3D-printing co-planar template; 3D-PNCT: 3D-printing non-co-planar template; CT: Computed tomography.

            region. Detailed information regarding patient positioning,   and needle trajectories to minimize potential damage to
            anesthesia methods, and template types for RSI in each   surrounding  critical  structures  while  achieving  optimal
            region can be found in Table 2.                    dose distribution in the target area. 34

            4. Discussion                                        Precise positioning and distribution of seed needles
                                                               are critical due to the intricate anatomical structures in
            Radiation dose at the tumor site can be increased by   the head and neck. Relying solely on image guidance may
            placing the radiation source near or within the tumor.
            This technique can also cause a rapid decline in dosage in   result in inaccuracies in the placement of the puncture
            the surrounding area. Brachytherapy has been recognized   needle or seeds, potentially harming surrounding tissues
            as an effective treatment modality by the Head and Neck   or  organs.  However,  the  use  of  3D-PT  significantly
            Working Group of the European Brachytherapy Group and   reduces the challenges associated with puncturing during
            the ABS. 30,31  The use of  I RSI offers significant advantages   RSI. These templates can effectively compensate for the
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            in the treatment of recurrent or metastatic malignant   lack of experience among novice operators and enhance
            tumors. 32,33  To ensure the accuracy and safety of  I RSI,   the consistency of the procedures. The implementation
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            meticulous pre-operative planning is essential. Radiation   of  3D-PT also ensures  accurate dose  determination.
            oncologists carefully design and optimize entry points   Compared to traditional puncture techniques, template


            Volume 2 Issue 4 (2024)                         6                              doi: 10.36922/arnm.4212
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